FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
Help Close All Open All
General Information
Term actin filament ID (Ontology) GO:0005884 (Gene Ontology)
Definition A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane.[ ISBN:0198506732 PubMed:10666339 ]
Also Known As "microfilament"
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Alleles (FBal)  PHENOTYPE_MANIFEST_IN      35
Genes (FBgn)  GO_CELLULAR_COMPONENT      21
Constructs (FBtp)  PHENOTYPE_MANIFEST_IN      13
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Alleles Gene Groups Genes Constructs
 actin filament (all annotations which use CV term, excluding "NOT" statements)      35      2     21     13
     actin filament | adult stage       3       --       --       3
     actin filament | cell autonomous | ectopic | somatic clone       1       --       --       --
     actin filament | ectopic       6       --       --       6
     actin filament | embryonic stage       3       --       --       --
     actin filament | embryonic stage 4 | germline clone       1       --       --       --
     actin filament | embryonic stage 4 | germline clone | non-rescuable maternal effect       2       --       --       --
     actin filament | embryonic stage 5       1       --       --       --
     actin filament | embryonic stage 5 | germline clone | maternal effect       1       --       --       --
     actin filament | embryonic stage 5 | maternal effect       2       --       --       --
     actin filament | embryonic stage | germline clone       3       --       --       --
     actin filament | female       1       --       --       --
     actin filament | germline clone       2       --       --       --
     actin filament | germline clone | maternal effect       2       --       --       --
     actin filament | heat sensitive       1       --       --       --
     actin filament | pupal stage | somatic clone       1       --       --       --
     actin filament | somatic clone       6       --       --       1
     actin filament | spermatogenesis       3       --       --       2
     actin filament | third instar larval stage       5       --       --       4
     colocalizes_with | actin filament       --       --      12       --
     is_active_in | actin filament       --       --       5       --
     located_in | actin filament       --       --       4       --
Spanning Tree (Parents/Children)
Only view relationship:
cytoskeleton
 |__actin cytoskeleton____________
 |__polymeric cytoskeletal fiber__|
supramolecular fiber              |
 |__polymeric cytoskeletal fiber__|
                                  actin filament  179 rec.
                                   |__actin filament branch point
                                   |__actin filament of cell cortex of cell tip
                                   |__actomyosin contractile ring actin filament 2 rec.
                                   |__filamentous actin 115 rec.
Spanning Tree View Settings
Parents/Children
View Depth
Show hierarchy levels: for parents, for children
hide Relationships
Is a polymeric cytoskeletal fiber
Part of actin cytoskeleton
hide Synonyms & Secondary IDs
Synonyms
  • "microfilament" EXACT
Secondary IDs
hide External Crossreferences & Linkouts
FMA:63850
NIF_Subcellular:sao1588493326
Wikipedia:Actin