FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term focal adhesion ID (Ontology) GO:0005925 (Gene Ontology)
Definition A cell-substrate junction that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments. In insects focal adhesion has also been referred to as hemi-adherens junction (HAJ).[ ISBN:0124325653 ISBN:0815316208 PubMed:10419689 PubMed:12191915 PubMed:15246682 PubMed:1643657 PubMed:16805308 PubMed:19197329 PubMed:23033047 PubMed:26923917 PubMed:28796323 PubMed:8314002 ]
Also Known As "connecting hemi-adherens junction" ; "focal contact" ; "HAJ" (for all, see Synonyms field below)
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Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_CELLULAR_COMPONENT      28
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Alleles Genes
 focal adhesion (all annotations which use CV term, excluding "NOT" statements)       --      28
     colocalizes_with | focal adhesion       --       1
     focal adhesion | pupal stage       1       --
     is_active_in | focal adhesion       --      16
     located_in | focal adhesion       --      22
Spanning Tree (Parents/Children)
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  anchoring junction
   |__cell-substrate junction
       |__focal adhesion  28 rec.
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Is a cell-substrate junction
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Synonyms
  • "adhesion plaque" RELATED[ PubMed:3332661 ]
    "connecting hemi-adherens junction" EXACT
    "focal contact" EXACT
    "HAJ" EXACT
    "hemi-adherens junction" EXACT
Secondary IDs
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Wikipedia:Focal_adhesion