FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term phosphatidylinositol 3-kinase complex ID (Ontology) GO:0005942 (Gene Ontology)
Definition A protein complex capable of phosphatidylinositol 3-kinase activity and containing subunits of any phosphatidylinositol 3-kinase (PI3K) enzyme. These complexes are divided in three classes (called I, II and III) that differ for their presence across taxonomic groups and for the type of their constituents. Catalytic subunits of phosphatidylinositol 3-kinase enzymes are present in all 3 classes; regulatory subunits of phosphatidylinositol 3-kinase enzymes are present in classes I and III; adaptor proteins have been observed in class II complexes and may be present in other classes too.[ PubMed:24587488 ]
Also Known As "1-phosphatidylinositol 3-kinase complex" ; "phosphoinositide 3-kinase complex" ; "PI3K complex"
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_CELLULAR_COMPONENT       1
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 Genes
 phosphatidylinositol 3-kinase complex (all annotations which use CV term, excluding "NOT" statements)       1
     part_of | phosphatidylinositol 3-kinase complex       1
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membrane
 |__extrinsic component of membrane_________________________________
 |__membrane protein complex________________________________________|
protein-containing complex                                          |
 |__membrane protein complex________________________________________|
cellular anatomical structure                                       |
 |__extrinsic component of membrane_________________________________|
transferase complex                                                 |
 |__transferase complex, transferring phosphorus-containing groups__|
                                                                    phosphatidylinositol 3-kinase complex  8 rec.
                                                                     |__phosphatidylinositol 3-kinase complex, class I 3 rec.
                                                                     |   |__phosphatidylinositol 3-kinase complex, class IA 3 rec.
                                                                     |   |__phosphatidylinositol 3-kinase complex, class IB
                                                                     |__phosphatidylinositol 3-kinase complex, class II
                                                                     |__phosphatidylinositol 3-kinase complex, class III 5 rec.
                                                                         |__phosphatidylinositol 3-kinase complex, class III, type I 5 rec.
                                                                         |__phosphatidylinositol 3-kinase complex, class III, type II 3 rec.
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Is a transferase complex, transferring phosphorus-containing groups
membrane protein complex
Part of extrinsic component of membrane
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Synonyms
  • "1-phosphatidylinositol 3-kinase complex" EXACT
    "phosphoinositide 3-kinase complex" EXACT
    "PI3-kinase p85-subunit alpha- PI3-kinase p110 complex" NARROW
    "PI3K complex" EXACT
    "PIK3C3-PIK3R4 complex" NARROW
    "PIK3CA-PIK3R1 complex" NARROW
Secondary IDs
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