FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
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General Information
Term phosphatidylinositol 3-kinase complex, class IB ID (Ontology) GO:0005944 (Gene Ontology)
Definition A class I phosphatidylinositol 3-kinase complex that possesses 1-phosphatidylinositol-4-phosphate 3-kinase activity; comprises a catalytic class IB phosphoinositide 3-kinase (PI3K) subunit and an associated regulatory subunit that is larger than, and unrelated to, the p85 proteins present in class IA complexes. Class IB PI3Ks are stimulated by G-proteins and do not interact with the SH2-domain containing adaptors that bind to Class IA PI3Ks.[ PubMed:9255069 PubMed:9759495 ]
Also Known As "1-phosphatidylinositol-4-phosphate 3-kinase, class IB complex" ; "class IB PI3K complex" ; "phosphoinositide 3-kinase complex, class IB"
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   |__phosphatidylinositol 3-kinase complex, class I
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Synonyms
  • "1-phosphatidylinositol-4-phosphate 3-kinase, class IB complex" EXACT
    "1-phosphatidylinositol-4-phosphate kinase, class IB complex" RELATED
    "class IB PI3K complex" EXACT
    "phosphoinositide 3-kinase complex, class IB" EXACT
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