FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
Help Close All Open All
General Information
Term pentose-phosphate shunt ID (Ontology) GO:0006098 (Gene Ontology)
Definition The metabolic process in which glucose-6-phosphate is oxidized to form carbon dioxide (CO2) and ribulose 5-phosphate, coupled to reduction of NADP+ to NADPH; ribulose 5-P then enters a series of reactions that can yield biosynthetic precursors (ribose-5-phosphate and erythrose-4-phosphate) and glycolytic intermediates (fructose-6-phosphate and glyceraldehyde-3-phosphate).[ ISBN:0198506732 ]
Also Known As "hexose monophosphate pathway" ; "pentose phosphate pathway" ; "pentose phosphate shunt" (for all, see Synonyms field below)
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
    Results list data from multiple species. Click on a button above and use the 'Filter by species' options on the resulting HitList to retrieve species-specific data.
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS       4
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 pentose-phosphate shunt (all annotations which use CV term, excluding "NOT" statements)       1      4
     involved_in | pentose-phosphate shunt       --       4
Spanning Tree (Parents/Children)
Only view relationship: 
generation of precursor metabolites and energy
 |__NADPH regeneration___________________________
NADP+ metabolic process                          |
 |__NADPH regeneration___________________________|
phosphate-containing compound metabolic process  |
 |__glucose 6-phosphate metabolic process________|
organophosphate metabolic process                |
 |__glucose 6-phosphate metabolic process________|
carbohydrate derivative metabolic process        |
 |__glucose 6-phosphate metabolic process________|
                                                 pentose-phosphate shunt  10 rec.
                                                  |__pentose-phosphate shunt, non-oxidative branch 5 rec.
                                                  |__pentose-phosphate shunt, oxidative branch 3 rec.
                                                  |__regulation of pentose-phosphate shunt 1 rec.
                                                      |__negative regulation of pentose-phosphate shunt
                                                      |__positive regulation of pentose-phosphate shunt 1 rec.
Spanning Tree View Settings
Parents/Children
View Depth
Show hierarchy levels: for parents, for children
hide Relationships
Is a NADPH regeneration
glucose 6-phosphate metabolic process
Part of
hide Synonyms & Secondary IDs
Synonyms
  • "hexose monophosphate pathway" EXACT
    "pentose phosphate pathway" EXACT
    "pentose phosphate shunt" EXACT
    "pentose-phosphate pathway" EXACT
Secondary IDs
hide External Crossreferences & Linkouts
KEGG_PATHWAY:map00030
MetaCyc:PENTOSE-P-PWY
Reactome:R-HSA-71336 "Pentose phosphate pathway"
Wikipedia:Pentose_phosphate_pathway