FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term base-excision repair, AP site formation ID (Ontology) GO:0006285 (Gene Ontology)
Definition The formation of an AP site, a deoxyribose sugar with a missing base, by DNA glycosylase which recognizes an altered base in DNA and catalyzes its hydrolytic removal. This sugar phosphate is the substrate recognized by the AP endonuclease, which cuts the DNA phosphodiester backbone at the 5' side of the altered site to leave a gap which is subsequently repaired.[ ISBN:0815316194 ]
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Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS       3
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 base-excision repair, AP site formation (all annotations which use CV term, excluding "NOT" statements)       3
     involved_in | base-excision repair, AP site formation       3
Spanning Tree (Parents/Children)
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DNA repair
 |__base-excision repair________
nucleic acid metabolic process  |
 |__DNA metabolic process_______|
                                base-excision repair, AP site formation  3 rec.
                                 |__base-excision repair, AP site formation via deaminated base removal
                                 |__depurination
                                 |__depyrimidination
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Is a DNA metabolic process
Part of base-excision repair
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Reactome:R-HSA-73929 "Base-Excision Repair, AP Site Formation"