FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term rRNA processing ID (Ontology) GO:0006364 (Gene Ontology)
Definition Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS      62
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Genes
 rRNA processing (all annotations which use CV term, excluding "NOT" statements)      62
     involved_in | rRNA processing      62
Spanning Tree (Parents/Children)
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gene expression
 |__RNA processing____________________
RNA metabolic process                 |
 |__rRNA metabolic process____________|
ribonucleoprotein complex biogenesis  |
 |__ribosome biogenesis_______________|
RNA biosynthetic process              |
 |__RNA processing____________________|
primary metabolic process             |
 |__RNA processing____________________|
                                      rRNA processing  159 rec.
                                       |__chloroplast rRNA processing
                                       |__cleavage of bicistronic rRNA transcript (SSU-rRNA, LSU-rRNA)
                                       |__endonucleolytic cleavage of tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA) 1 rec.
                                       |   |__cleavage between 2S rRNA and LSU-rRNA of tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)
                                       |   |__cleavage between 5.8S rRNA and 2S rRNA of tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)
                                       |   |__cleavage between SSU-rRNA and 5.8S rRNA of tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)
                                       |__endonucleolytic cleavage of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)
                                       |   |__endonucleolytic cleaveage between 4.5S rRNA and 5S rRNA of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)
                                       |   |__endonucleolytic cleaveage between LSU-rRNA and 4.5S rRNA of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)
                                       |   |__endonucleolytic cleaveage between SSU-rRNA and LSU-rRNA of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)
                                       |__endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 16 rec.
                                       |   |__cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 1 rec.
                                       |   |__endonucleolytic cleavage in 3'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
                                       |   |__endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 8 rec.
                                       |   |__endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 11 rec.
                                       |   |__endonucleolytic cleavage in ITS1 upstream of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
                                       |   |__endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 1 rec.
                                       |   |__endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 8 rec.
                                       |__endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 5S)
                                       |   |__endonucleolytic cleavage between LSU-rRNA and 5S rRNA of tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 5S)
                                       |   |__endonucleolytic cleavage between SSU-rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 5S)
                                       |__maturation of 2S rRNA
                                       |   |__cleavage between 2S rRNA and LSU-rRNA of tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)
                                       |   |__cleavage between 5.8S rRNA and 2S rRNA of tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)
                                       |__maturation of 4.5S rRNA
                                       |__maturation of 5.8S rRNA 29 rec.
                                       |   |__maturation of 5.8S rRNA from tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)(+)
                                       |   |__maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(+) 20 rec.
                                       |__maturation of 5S rRNA 1 rec.
                                       |   |__generation of mature 3'-end of 5S rRNA generated by RNA polymerase III
                                       |   |__maturation of 5S rRNA from tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
                                       |__maturation of LSU-rRNA 27 rec.
                                       |   |__maturation of LSU-rRNA from tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)(+)
                                       |   |__maturation of LSU-rRNA from tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)
                                       |   |__maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(+) 18 rec.
                                       |   |__maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA,5S)(+)
                                       |__maturation of SSU-rRNA 50 rec.
                                       |   |__maturation of SSU-rRNA from tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)(+)
                                       |   |__maturation of SSU-rRNA from tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)
                                       |   |__maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(+) 32 rec.
                                       |   |__maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA,5S)(+)
                                       |   |__rRNA acetylation involved in maturation of SSU-rRNA 2 rec.
                                       |__regulation of rRNA processing 2 rec.
                                       |   |__negative regulation of rRNA processing
                                       |   |__positive regulation of rRNA processing 2 rec.
                                       |__rRNA 3'-end processing 10 rec.
                                       |   |__endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 1 rec.
                                       |   |__exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 6 rec.
                                       |   |__generation of mature 3'-end of 5S rRNA generated by RNA polymerase III
                                       |   |__generation of mature 3'-end of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
                                       |__rRNA 5'-end processing 8 rec.
                                       |   |__endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 8 rec.
                                       |   |__exonucleolytic trimming to generate mature 5'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
                                       |   |__generation of mature 5'-end of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
                                       |__rRNA modification 30 rec.
                                       |   |__cotranscriptional mitochondrial rRNA nucleotide insertion
                                       |   |__rRNA acetylation(+) 2 rec.
                                       |   |__rRNA methylation(+) 19 rec.
                                       |   |__rRNA pseudouridine synthesis(+) 8 rec.
                                       |__snoRNA release from pre-rRNA
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Is a RNA processing
rRNA metabolic process
Part of ribosome biogenesis
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Synonyms
  • "35S primary transcript processing" NARROW
Secondary IDs
hide External Crossreferences & Linkouts
Reactome:R-HSA-72312 "rRNA processing"