FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
Help Close All Open All
General Information
Term 7-methylguanosine mRNA capping ID (Ontology) GO:0006370 (Gene Ontology)
Definition The sequence of enzymatic reactions by which the mRNA 5' cap structure, an inverted 7-methylguanosine linked via a 5'-5' triphosphate bridge (m7G(5')ppp(5')X) to the first transcribed residue, is added to a nascent transcript. Additional methylation can occur on the ribose sugars of the first and second nucleotides adjacent to the m7G nRNA cap. These methylations are often referred to as N6,2'-O-dimethyladenosine (m6,2A) and N6,2'-O-dimethylguanosine (m6,2G), respectively.[ PubMed:9266685 ]
Also Known As "5' mRNA capping" ; "5'-end mRNA processing" ; "mRNA capping"
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
    Results list data from multiple species. Click on a button above and use the 'Filter by species' options on the resulting HitList to retrieve species-specific data.
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS       5
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Genes
 7-methylguanosine mRNA capping (all annotations which use CV term, excluding "NOT" statements)       5
     involved_in | 7-methylguanosine mRNA capping       5
Spanning Tree (Parents/Children)
Only view relationship:
RNA processing
 |__mRNA processing________________
mRNA metabolic process             |
 |__mRNA processing________________|
RNA capping                        |
 |__7-methylguanosine RNA capping__|
                                   7-methylguanosine mRNA capping  5 rec.
Spanning Tree View Settings
Parents/Children
View Depth
Show hierarchy levels: for parents, for children
hide Relationships
Is a mRNA processing
7-methylguanosine RNA capping
Part of
hide Synonyms & Secondary IDs
Synonyms
  • "5' end capping" BROAD
    "5' mRNA capping" EXACT
    "5'-end mRNA processing" EXACT
    "5'-end processing" BROAD
    "mRNA capping" EXACT
Secondary IDs
hide External Crossreferences & Linkouts
Reactome:R-HSA-72086 "mRNA Capping"