FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term regulation of translational initiation ID (Ontology) GO:0006446 (Gene Ontology)
Definition Any process that modulates the frequency, rate or extent of translational initiation.
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Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS      13
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Genes
 regulation of translational initiation (all annotations which use CV term, excluding "NOT" statements)      13
     involved_in | regulation of translational initiation      13
Spanning Tree (Parents/Children)
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translation
 |__translational initiation________________________
 |__regulation of translation_______________________|
metabolic process                                   |
 |__translational initiation________________________|
post-transcriptional regulation of gene expression  |
 |__regulation of translation_______________________|
regulation of protein metabolic process             |
 |__regulation of translation_______________________|
                                                    regulation of translational initiation  32 rec.
                                                     |__negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation
                                                     |__negative regulation of translational initiation 14 rec.
                                                     |   |__negative regulation of cytoplasmic translational initiation(+)
                                                     |   |__negative regulation of formation of translation initiation ternary complex
                                                     |   |__negative regulation of mitochondrial translational initiation
                                                     |   |__negative regulation of translational initiation by iron
                                                     |   |__negative regulation of translational initiation in response to stress(+) 1 rec.
                                                     |__positive regulation of translational initiation 5 rec.
                                                     |   |__positive regulation of cytoplasmic translational initiation(+) 1 rec.
                                                     |   |__positive regulation of mitochondrial translational initiation
                                                     |   |__positive regulation of translational initiation by iron
                                                     |   |__positive regulation of translational initiation in response to stress(+) 1 rec.
                                                     |__regulation of cytoplasmic translational initiation 2 rec.
                                                     |   |__negative regulation of cytoplasmic translational initiation(+)
                                                     |   |__positive regulation of cytoplasmic translational initiation(+) 1 rec.
                                                     |   |__regulation of cap-dependent translational initiation(+)
                                                     |   |__regulation of cap-independent translational initiation(+)
                                                     |   |__regulation of cytoplasmic translational initiation in response to stress(+)
                                                     |   |__regulation of formation of translation preinitiation complex(+) 1 rec.
                                                     |__regulation of eIF2 alpha phosphorylation by dsRNA
                                                     |__regulation of eIF2 alpha phosphorylation by heme
                                                     |__regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation
                                                     |__regulation of mitochondrial translational initiation
                                                     |   |__negative regulation of mitochondrial translational initiation
                                                     |   |__positive regulation of mitochondrial translational initiation
                                                     |__regulation of translational initiation by iron
                                                     |   |__negative regulation of translational initiation by iron
                                                     |   |__positive regulation of translational initiation by iron
                                                     |__regulation of translational initiation by tRNA modification
                                                     |__regulation of translational initiation in response to stress
                                                         |__negative regulation of translation in response to oxidative stress
                                                         |__regulation of cytoplasmic translational initiation in response to stress(+)
                                                         |__regulation of translation initiation in response to endoplasmic reticulum stress(+)
                                                         |__regulation of translational initiation by eIF2 alpha dephosphorylation(+)
                                                         |__regulation of translational initiation by eIF2 alpha phosphorylation(+)
                                                         |__regulation of translational initiation in response to osmotic stress(+)
                                                         |__regulation of translational initiation in response to starvation(+)
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