FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term protein methylation ID (Ontology) GO:0006479 (Gene Ontology)
Definition The addition of a methyl group to a protein amino acid. A methyl group is derived from methane by the removal of a hydrogen atom.
Also Known As "protein amino acid methylation"
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Annotations
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 Gene Groups
 protein methylation (all annotations which use CV term, excluding "NOT" statements)       1
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methylation
 |__macromolecule methylation__
protein modification process   |
 |__protein alkylation_________|
macromolecule modification     |
 |__macromolecule methylation__|
                               protein methylation  9 rec.
                                |__C-terminal protein methylation
                                |__N-terminal protein amino acid methylation
                                |   |__N-terminal peptidyl-alanine methylation(+)
                                |   |__N-terminal peptidyl-glycine methylation
                                |   |__N-terminal peptidyl-proline methylation(+)
                                |   |__N-terminal peptidyl-serine methylation(+)
                                |__peptidyl-arginine methylation 3 rec.
                                |   |__peptidyl-arginine N-methylation(+)
                                |__peptidyl-cysteine methylation
                                |__peptidyl-glutamine methylation
                                |__peptidyl-histidine methylation 1 rec.
                                |   |__peptidyl-histidine methylation, to form tele-methylhistidine
                                |__peptidyl-lysine methylation 4 rec.
                                    |__peptidyl-lysine dimethylation
                                    |__peptidyl-lysine monomethylation
                                    |__peptidyl-lysine trimethylation
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Is a protein alkylation
macromolecule methylation
Part of
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Synonyms
  • "protein amino acid methylation" EXACT
Secondary IDs
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Reactome:R-HSA-8876725 "Protein methylation"