FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term protein O-linked glycosylation ID (Ontology) GO:0006493 (Gene Ontology)
Definition A glycoprotein biosynthetic process starting with the covalent linkage of carbohydrate or carbohydrate derivative unit via a glycosidic bond to the oxygen atom of a serine, threonine, hydroxylysine, hydroxyproline or tyrosine side chain in a protein, which can be further elongated with the sequential addition of sugar units resulting in the formation of a protein O-linked glycan.[ PubMed:33775405 ]
Also Known As "protein amino acid O-linked glycosylation"
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS      20
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 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 protein O-linked glycosylation (all annotations which use CV term, excluding "NOT" statements)       4     20
     involved_in | protein O-linked glycosylation       --      20
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macromolecule biosynthetic process____________
glycoprotein metabolic process________________|
carbohydrate derivative biosynthetic process__|
                                              glycoprotein biosynthetic process
                                               |__protein O-linked glycosylation  76 rec.
                                                   |__protein O-linked glycosylation via arabinose
                                                   |__protein O-linked glycosylation via fucose 4 rec.
                                                   |__protein O-linked glycosylation via galactose 3 rec.
                                                   |__protein O-linked glycosylation via glucose 5 rec.
                                                   |__protein O-linked glycosylation via mannose 12 rec.
                                                   |   |__keratan sulfate-III proteoglycan biosynthetic process
                                                   |__protein O-linked glycosylation via N-acetyl-galactosamine 19 rec.
                                                   |   |__keratan sulfate-II proteoglycan biosynthetic process
                                                   |__protein O-linked glycosylation via xylose 28 rec.
                                                   |   |__chondroitin sulfate proteoglycan biosynthetic process(+) 14 rec.
                                                   |   |__dermatan sulfate proteoglycan biosynthetic process(+) 4 rec.
                                                   |   |__glycosaminoglycan-protein linkage region biosynthetic process 4 rec.
                                                   |   |__heparan sulfate proteoglycan biosynthetic process(+) 19 rec.
                                                   |   |__heparin proteoglycan biosynthetic process(+) 4 rec.
                                                   |__regulation of protein O-linked glycosylation
                                                       |__negative regulation of protein O-linked glycosylation
                                                       |__positive regulation of protein O-linked glycosylation(+)
                                                       |__regulation of heparan sulfate proteoglycan biosynthetic process(+)
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Is a glycoprotein biosynthetic process
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Synonyms
  • "protein amino acid O-linked glycosylation" EXACT
Secondary IDs
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Reactome:R-HSA-5173105 "O-linked glycosylation"
RESID:AA0153
RESID:AA0154
RESID:AA0155
RESID:AA0157
RESID:AA0212