FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
Help Close All Open All
General Information
Term GPI anchor biosynthetic process ID (Ontology) GO:0006506 (Gene Ontology)
Definition The chemical reactions and pathways resulting in the formation of a glycosylphosphatidylinositol (GPI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The phosphatidylinositol group is linked via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked to the protein via an ethanolamine phosphate group, its amino group forming an amide linkage with the C-terminal carboxyl of the protein. Some GPI anchors have variants on this canonical linkage.[ ISBN:0198547684 ]
Also Known As "glycosylphosphatidylinositol biosynthesis" ; "glycosylphosphatidylinositol biosynthetic process" ; "GPI anchor anabolism" (for all, see Synonyms field below)
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
    Results list data from multiple species. Click on a button above and use the 'Filter by species' options on the resulting HitList to retrieve species-specific data.
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS      30
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 GPI anchor biosynthetic process (all annotations which use CV term, excluding "NOT" statements)       7     30
     involved_in | GPI anchor biosynthetic process       --      30
Spanning Tree (Parents/Children)
Only view relationship: 
glycolipid metabolic process
 |__GPI anchor metabolic process_______________
 |__glycolipid biosynthetic process____________|
membrane lipid biosynthetic process            |
 |__glycolipid biosynthetic process____________|
glycerophospholipid biosynthetic process       |
 |__phosphatidylinositol biosynthetic process__|
phosphatidylinositol metabolic process         |
 |__GPI anchor metabolic process_______________|
 |__phosphatidylinositol biosynthetic process__|
protein maturation                             |
 |__GPI anchored protein biosynthesis__________|
carbohydrate derivative biosynthetic process   |
 |__glycolipid biosynthetic process____________|
                                               GPI anchor biosynthetic process  37 rec.
Spanning Tree View Settings
Parents/Children
View Depth
Show hierarchy levels: for parents, for children
hide Relationships
Is a GPI anchor metabolic process
phosphatidylinositol biosynthetic process
glycolipid biosynthetic process
Part of GPI anchored protein biosynthesis
hide Synonyms & Secondary IDs
Synonyms
  • "glycosylphosphatidylinositol biosynthesis" EXACT
    "glycosylphosphatidylinositol biosynthetic process" EXACT
    "GPI anchor anabolism" EXACT
    "GPI anchor biosynthesis" EXACT
    "GPI anchor formation" EXACT
    "GPI anchor synthesis" EXACT
    "GPI/GSI anchor biosynthesis" BROAD
    "GPI/GSI anchor biosynthetic process" BROAD
Secondary IDs
hide External Crossreferences & Linkouts
Reactome:R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)"