General Information
Term	creatine biosynthetic process	ID (Ontology)	GO:0006601 (Gene Ontology)
Definition	The chemical reactions and pathways resulting in the formation of creatine, N-[amino(imino)methyl]-N-methylglycine. Creatine is formed by a process beginning with amidino group transfer from L-arginine to glycine to form guanidinoacetate, followed by methyl group transfer from S-adenosyl-L-methionine to guanidinoacetate; it is then is phosphorylated to form a pool that stores high energy phosphate for the replenishment of ATP during periods of high, or fluctuating energy demand. In animals, most creatine is transported to and used in muscle.
Also Known As	"creatine anabolism" ; "creatine biosynthesis" ; "creatine formation" (for all, see Synonyms field below)
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Records annotated with this exact term (annotations to child terms are NOT included)
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Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
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General Information

Term

creatine biosynthetic process

ID (Ontology)

GO:0006601 (Gene Ontology)

Definition

The chemical reactions and pathways resulting in the formation of creatine, N-[amino(imino)methyl]-N-methylglycine. Creatine is formed by a process beginning with amidino group transfer from L-arginine to glycine to form guanidinoacetate, followed by methyl group transfer from S-adenosyl-L-methionine to guanidinoacetate; it is then is phosphorylated to form a pool that stores high energy phosphate for the replenishment of ATP during periods of high, or fluctuating energy demand. In animals, most creatine is transported to and used in muscle.

Also Known As

"creatine anabolism" ; "creatine biosynthesis" ; "creatine formation" (for all, see Synonyms field below)

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

No relevant statements available

modified amino acid metabolic process
 |__creatine metabolic process________________
 |__modified amino acid biosynthetic process__|
biosynthetic process                          |
 |__modified amino acid biosynthetic process__|
monocarboxylic acid metabolic process         |
 |__creatine metabolic process________________|
 |__monocarboxylic acid biosynthetic process__|
carboxylic acid biosynthetic process          |
 |__monocarboxylic acid biosynthetic process__|
                                              creatine biosynthetic process

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Is a	creatine metabolic process modified amino acid biosynthetic process monocarboxylic acid biosynthetic process
Part of
Synonyms & Secondary IDs
Synonyms
	"creatine anabolism" EXACT "creatine biosynthesis" EXACT "creatine formation" EXACT "creatine synthesis" EXACT
Secondary IDs

External Crossreferences & Linkouts
	MetaCyc:GLYCGREAT-PWY

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Parents/Children
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Relationships

Is a

creatine metabolic process
modified amino acid biosynthetic process
monocarboxylic acid biosynthetic process

Part of

Synonyms & Secondary IDs

Synonyms

"creatine anabolism" EXACT
"creatine biosynthesis" EXACT
"creatine formation" EXACT
"creatine synthesis" EXACT

Secondary IDs

External Crossreferences & Linkouts

MetaCyc:GLYCGREAT-PWY