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General Information
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| Term |
SRP-dependent cotranslational protein targeting to membrane, translocation |
ID (Ontology) |
GO:0006616 (Gene Ontology) |
| Definition |
The process during cotranslational membrane targeting wherein proteins move across a membrane. SRP and its receptor initiate the transfer of the nascent chain across the endoplasmic reticulum (ER) membrane; they then dissociate from the chain, which is transferred to a set of transmembrane proteins, collectively called the translocon. Once the nascent chain translocon complex is assembled, the elongating chain passes directly from the large ribosomal subunit into the centers of the translocon, a protein-lined channel within the membrane. The growing chain is never exposed to the cytosol and does not fold until it reaches the ER lumen.[ ISBN:0716731363 ] |
| Also Known As |
"SRP-dependent cotranslational membrane targeting, translocation" ; "SRP-dependent cotranslational protein-membrane targeting, translocation" ; "translocation during SRP-dependent cotranslational protein targeting to membrane" |
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Links to External Ontologies
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QuickGO data AmiGO data
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Annotations
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Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
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| Data Class | Field | Records |
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| Genes (FBgn) | GO_BIOLOGICAL_PROCESS | 7 |
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Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
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| Full annotation statements | Relevant FlyBase reports |
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| Gene Groups | Genes |
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SRP-dependent cotranslational protein targeting to membrane, translocation (all annotations which use CV term, excluding "NOT" statements) | 5 | 7 | involved_in | SRP-dependent cotranslational protein targeting to membrane, translocation | -- | 7 |
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Relationships
