FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term glutathione biosynthetic process ID (Ontology) GO:0006750 (Gene Ontology)
Definition The chemical reactions and pathways resulting in the formation of glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins.[ ISBN:0198506732 ]
Also Known As "glutathione anabolism" ; "glutathione biosynthesis" ; "glutathione formation" (for all, see Synonyms field below)
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS       5
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Relevant FlyBase reports
 Gene Groups Genes
 glutathione biosynthetic process (all annotations which use CV term, excluding "NOT" statements)       1      5
     involved_in | glutathione biosynthetic process       --       5
Spanning Tree (Parents/Children)
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modified amino acid metabolic process
 |__glutathione metabolic process______________
 |__modified amino acid biosynthetic process___|
sulfur compound metabolic process              |
 |__glutathione metabolic process______________|
 |__sulfur compound biosynthetic process_______|
biosynthetic process                           |
 |__modified amino acid biosynthetic process___|
 |__amide biosynthetic process_________________|
 |__sulfur compound biosynthetic process_______|
peptide biosynthetic process                   |
 |__nonribosomal peptide biosynthetic process__|
amide metabolic process                        |
 |__glutathione metabolic process______________|
 |__amide biosynthetic process_________________|
                                               glutathione biosynthetic process  6 rec.
                                                |__regulation of glutathione biosynthetic process
                                                    |__negative regulation of glutathione biosynthetic process
                                                    |__positive regulation of glutathione biosynthetic process
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Is a glutathione metabolic process
nonribosomal peptide biosynthetic process
modified amino acid biosynthetic process
amide biosynthetic process
sulfur compound biosynthetic process
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Synonyms
  • "glutathione anabolism" EXACT
    "glutathione biosynthesis" EXACT
    "glutathione formation" EXACT
    "glutathione synthesis" EXACT
Secondary IDs
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MetaCyc:GLUTATHIONESYN-PWY
Reactome:R-HSA-174403 "Glutathione synthesis and recycling"