FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term heme biosynthetic process ID (Ontology) GO:0006783 (Gene Ontology)
Definition The chemical reactions and pathways resulting in the formation of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, from less complex precursors.[ PubMed:11788607 ]
Also Known As "haem biosynthesis" ; "haem biosynthetic process" ; "heme anabolism" (for all, see Synonyms field below)
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS      12
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 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 heme biosynthetic process (all annotations which use CV term, excluding "NOT" statements)       2     12
     involved_in | heme biosynthetic process       --      12
Spanning Tree (Parents/Children)
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porphyrin-containing compound metabolic process
 |__porphyrin-containing compound biosynthetic process__
 |__heme metabolic process______________________________|
tetrapyrrole biosynthetic process                       |
 |__porphyrin-containing compound biosynthetic process__|
pigment metabolic process                               |
 |__heme metabolic process______________________________|
 |__pigment biosynthetic process________________________|
                                                        heme biosynthetic process  15 rec.
                                                         |__heme A biosynthetic process 3 rec.
                                                         |__heme B biosynthetic process
                                                         |__heme C biosynthetic process
                                                         |__heme O biosynthetic process
                                                         |__siroheme biosynthetic process
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Is a porphyrin-containing compound biosynthetic process
heme metabolic process
pigment biosynthetic process
Part of
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Synonyms
  • "haem biosynthesis" EXACT
    "haem biosynthetic process" EXACT
    "heme anabolism" EXACT
    "heme biosynthesis" EXACT
    "heme formation" EXACT
    "heme synthesis" EXACT
Secondary IDs
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MetaCyc:HEMESYN2-PWY
Reactome:R-HSA-189451 "Heme biosynthesis"