FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term exocytosis ID (Ontology) GO:0006887 (Gene Ontology)
Definition A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle. Exocytosis can occur either by full fusion, when the vesicle collapses into the plasma membrane, or by a kiss-and-run mechanism that involves the formation of a transient contact, a pore, between a granule (for example of chromaffin cells) and the plasma membrane. The latter process most of the time leads to only partial secretion of the granule content. Exocytosis begins with steps that prepare vesicles for fusion with the membrane (tethering and docking) and ends when molecules are secreted from the cell.[ ISBN:0716731363 PubMed:22323285 ]
Also Known As "vesicle exocytosis"
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS      47
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 Full annotation statements 
Relevant FlyBase reports
 Genes
 exocytosis (all annotations which use CV term, excluding "NOT" statements)      47
     involved_in | exocytosis      47
Spanning Tree (Parents/Children)
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transport
 |__vesicle-mediated transport__
cellular process                |
 |__vesicle-mediated transport__|
secretion                       |
 |__secretion by cell___________|
export from cell                |
 |__secretion by cell___________|
                                exocytosis  105 rec.
                                 |__autophagosome-dependent secretion
                                 |__constitutive secretory pathway
                                 |   |__regulation of constitutive secretory pathway(+)
                                 |__exocytic insertion of neurotransmitter receptor to postsynaptic membrane
                                 |   |__regulation of exocytic insertion of neurotransmitter receptor to postsynaptic membrane
                                 |__exocytic process 46 rec.
                                 |   |__dense core granule priming 1 rec.
                                 |   |__exocyst assembly(+)
                                 |   |__histamine secretion by basophil
                                 |   |__histamine secretion by mast cell(+)
                                 |   |__histamine secretion by platelet
                                 |   |__pore formation during contractile vacuole discharge
                                 |   |__protein secretion by platelet
                                 |   |__serotonin secretion by basophil
                                 |   |__serotonin secretion by mast cell
                                 |   |__serotonin secretion by platelet
                                 |   |__synaptic vesicle priming(+) 16 rec.
                                 |   |__synaptic vesicle targeting 7 rec.
                                 |   |__vesicle docking involved in exocytosis(+) 24 rec.
                                 |   |__vesicle fusion to plasma membrane(+) 18 rec.
                                 |   |__vesicle tethering involved in exocytosis(+) 6 rec.
                                 |__exosomal secretion 10 rec.
                                 |   |__multivesicular body fusion to apical plasma membrane 2 rec.
                                 |   |__regulation of exosomal secretion(+)
                                 |__regulated exocytosis 65 rec.
                                 |   |__calcium-ion regulated exocytosis(+) 16 rec.
                                 |   |__contractile vacuole discharge(+)
                                 |   |__leukocyte degranulation(+)
                                 |   |__platelet degranulation(+)
                                 |   |__regulation of regulated secretory pathway(+) 17 rec.
                                 |   |__synaptic vesicle exocytosis(+) 59 rec.
                                 |__regulation of exocytosis 22 rec.
                                     |__negative regulation of exocytosis(+) 3 rec.
                                     |__positive regulation of exocytosis(+) 7 rec.
                                     |__regulation of constitutive secretory pathway(+)
                                     |__regulation of exocytic insertion of neurotransmitter receptor to postsynaptic membrane
                                     |__regulation of exosomal secretion(+)
                                     |__regulation of regulated secretory pathway(+) 17 rec.
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Is a vesicle-mediated transport
secretion by cell
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Synonyms
  • "nonselective vesicle exocytosis" RELATED
    "vesicle exocytosis" EXACT
Secondary IDs
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Wikipedia:Exocytosis