FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term autophagy ID (Ontology) GO:0006914 (Gene Ontology)
Definition The cellular catabolic process in which cells digest cellular materials, such as organelles and other macromolecular constituents, or non-self materials such as intracellular pathogens. Autophagy serves to provide essential nutrients under conditions of cellular stress; or can remodel intracellular structures during cell differentiation.[ ISBN:0198547684 PubMed:11099404 PubMed:29455577 PubMed:9412464 ]
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS      32
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 autophagy (all annotations which use CV term, excluding "NOT" statements)       5     32
     involved_in | autophagy       --      32
 NOT | involved_in | autophagy       --       1
Spanning Tree (Parents/Children)
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metabolic process
 |__catabolic process_______________________
cellular process                            |
 |__process utilizing autophagic mechanism__|
                                            autophagy  226 rec.
                                             |__autophagy of mitochondrion 41 rec.
                                             |   |__micromitophagy
                                             |   |__mitophagy(+) 35 rec.
                                             |   |__mitophagy by internal vacuole formation 1 rec.
                                             |   |__regulation of autophagy of mitochondrion(+) 14 rec.
                                             |__autophagy of peroxisome 7 rec.
                                             |   |__micropexophagy
                                             |   |__pexophagy 7 rec.
                                             |__chaperone-mediated autophagy
                                             |   |__chaperone-mediated autophagy translocation complex assembly
                                             |   |__protein targeting to lysosome involved in chaperone-mediated autophagy
                                             |   |__regulation of chaperone-mediated autophagy(+)
                                             |__crinophagy 11 rec.
                                             |   |__secretory granule-lysosome fusion 8 rec.
                                             |__macroautophagy 160 rec.
                                             |   |__aggrephagy(+) 4 rec.
                                             |   |__amphisome-lysosome fusion
                                             |   |__autophagosome maturation(+) 34 rec.
                                             |   |__autophagosome organization(+) 45 rec.
                                             |   |__autophagosome-endosome fusion
                                             |   |__autophagosome-lysosome fusion 10 rec.
                                             |   |__glycophagy 13 rec.
                                             |   |__lipophagy(+) 10 rec.
                                             |   |__lysophagy
                                             |   |__mitophagy(+) 35 rec.
                                             |   |__nucleophagy(+) 16 rec.
                                             |   |__pexophagy 7 rec.
                                             |   |__proteaphagy
                                             |   |__regulation of macroautophagy(+) 64 rec.
                                             |   |__reticulophagy(+) 18 rec.
                                             |   |__ribophagy 1 rec.
                                             |   |__xenophagy(+)
                                             |__microautophagy 12 rec.
                                             |   |__late endosomal microautophagy 1 rec.
                                             |   |__microlipophagy(+)
                                             |   |__micromitophagy
                                             |   |__micropexophagy
                                             |   |__piecemeal microautophagy of the nucleus 11 rec.
                                             |__protein targeting to vacuole involved in autophagy
                                             |   |__protein targeting to lysosome involved in chaperone-mediated autophagy
                                             |   |__regulation of protein targeting to vacuole involved in autophagy(+)
                                             |__regulation of autophagy 115 rec.
                                                 |__negative regulation of autophagy(+) 31 rec.
                                                 |__positive regulation of autophagy(+) 64 rec.
                                                 |__regulation of autophagy of mitochondrion(+) 14 rec.
                                                 |__regulation of chaperone-mediated autophagy(+)
                                                 |__regulation of macroautophagy(+) 64 rec.
                                                 |__regulation of microlipophagy
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Is a catabolic process
process utilizing autophagic mechanism
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Reactome:R-HSA-9612973 "Autophagy"
Wikipedia:Autophagy_(cellular)