FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term activation-induced cell death of T cells ID (Ontology) GO:0006924 (Gene Ontology)
Definition A T cell apoptotic process that occurs towards the end of the expansion phase following the initial activation of mature T cells by antigen and is triggered by T cell receptor stimulation and signals transmitted via various surface-expressed members of the TNF receptor family such as Fas ligand, Fas, and TNF and the p55 and p75 TNF receptors.[ ISBN:0781765196 PubMed:12414721 PubMed:12752672 ]
Also Known As "activation-induced cell death of T lymphocytes" ; "activation-induced cell death of T-cells" ; "activation-induced cell death of T-lymphocytes"
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lymphocyte homeostasis
 |__T cell homeostasis________
lymphocyte apoptotic process  |
 |__T cell apoptotic process__|
                              activation-induced cell death of T cells
                               |__regulation of activation-induced cell death of T cells
                                   |__negative regulation of activation-induced cell death of T cells
                                   |__positive regulation of activation-induced cell death of T cells
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Is a T cell apoptotic process
Part of T cell homeostasis
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Synonyms
  • "activated T cell apoptosis" BROAD
    "activation-induced cell death of T lymphocytes" EXACT
    "activation-induced cell death of T-cells" EXACT
    "activation-induced cell death of T-lymphocytes" EXACT
    "AICD" BROAD
    "antigen-driven apoptosis" BROAD
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