FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
Help Close All Open All
General Information
Term DNA damage response ID (Ontology) GO:0006974 (Gene Ontology)
Definition Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
Also Known As "cellular DNA damage response" ; "cellular response to DNA damage stimulus" ; "response to genotoxic stress"
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
    Results list data from multiple species. Click on a button above and use the 'Filter by species' options on the resulting HitList to retrieve species-specific data.
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS      49
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Genes
 DNA damage response (all annotations which use CV term, excluding "NOT" statements)      49
     involved_in | DNA damage response      49
Spanning Tree (Parents/Children)
Only view relationship:
response to stress_____________
cellular response to stimulus__|
                               cellular response to stress
                                |__DNA damage response  294 rec.
                                    |__DNA damage tolerance 17 rec.
                                    |   |__error-free postreplication DNA repair(+)
                                    |   |__translesion synthesis(+) 13 rec.
                                    |__DNA repair 213 rec.
                                    |   |__base-excision repair(+) 14 rec.
                                    |   |__chromosomal 5-methylcytosine DNA demethylation, oxidative deamination pathway
                                    |   |__DNA alkylation repair 2 rec.
                                    |   |__DNA replication proofreading 7 rec.
                                    |   |__double-strand break repair(+) 109 rec.
                                    |   |__interstrand cross-link repair(+) 16 rec.
                                    |   |__mismatch repair(+) 14 rec.
                                    |   |__mitochondrial DNA repair 1 rec.
                                    |   |__non-photoreactive DNA repair
                                    |   |__nucleotide-excision repair(+) 28 rec.
                                    |   |__protein-DNA covalent cross-linking repair 3 rec.
                                    |   |__pyrimidine dimer repair(+) 2 rec.
                                    |   |__recombinational repair(+) 66 rec.
                                    |   |__single strand break repair(+) 3 rec.
                                    |   |__UV-damage excision repair 3 rec.
                                    |   |__viral DNA repair
                                    |__intrinsic apoptotic signaling pathway in response to DNA damage 15 rec.
                                    |   |__intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 7 rec.
                                    |__signal transduction in response to DNA damage 42 rec.
                                    |   |__DNA damage checkpoint signaling(+) 38 rec.
                                    |   |__DNA damage response, signal transduction by p53 class mediator 5 rec.
                                    |   |__DNA damage response, signal transduction resulting in transcription
                                    |__SOS response
                                    |__telomere maintenance in response to DNA damage 4 rec.
                                        |__protection from non-homologous end joining at telomere 4 rec.
                                        |__telomere maintenance via base-excision repair
Spanning Tree View Settings
Parents/Children
View Depth
Show hierarchy levels: for parents, for children
hide Relationships
Is a cellular response to stress
Part of
hide Synonyms & Secondary IDs
Synonyms
  • "cellular DNA damage response" EXACT
    "cellular response to DNA damage stimulus" EXACT
    "response to DNA damage stimulus" BROAD
    "response to genotoxic stress" EXACT
Secondary IDs
hide External Crossreferences & Linkouts