FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term ER-nucleus signaling pathway ID (Ontology) GO:0006984 (Gene Ontology)
Definition The series of molecular signals that conveys information from the endoplasmic reticulum to the nucleus, usually resulting in a change in transcriptional regulation.
Also Known As "endoplasmic reticulum to nucleus signaling pathway" ; "endoplasmic reticulum-nuclear signaling pathway" ; "ER to nucleus signaling pathway" (for all, see Synonyms field below)
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  signal transduction
   |__intracellular signal transduction
       |__ER-nucleus signaling pathway  7 rec.
           |__ATF6-mediated unfolded protein response
           |   |__regulation of ATF6-mediated unfolded protein response(+)
           |__ER overload response
           |   |__detection of endoplasmic reticulum overloading
           |   |__positive regulation of autophagy in response to ER overload
           |__PERK-mediated unfolded protein response 2 rec.
           |   |__regulation of PERK-mediated unfolded protein response(+)
           |__SREBP signaling pathway 5 rec.
               |__regulation of SREBP signaling pathway(+) 1 rec.
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Is a intracellular signal transduction
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Synonyms
  • "endoplasmic reticulum to nucleus signaling pathway" EXACT
    "endoplasmic reticulum-nuclear signaling pathway" EXACT
    "ER to nucleus signaling pathway" EXACT
    "ER to nucleus signalling pathway" EXACT
    "ER-nuclear signaling pathway" EXACT
    "ER-nuclear signalling pathway" EXACT
Secondary IDs
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