FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term cell surface receptor protein serine/threonine kinase signaling pathway ID (Ontology) GO:0007178 (Gene Ontology)
Definition The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of the target cell where the receptor possesses serine/threonine kinase activity, and ending with the regulation of a downstream cellular process, e.g. transcription.
Also Known As "transmembrane receptor protein serine/threonine kinase signalling pathway"
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS      10
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 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 cell surface receptor protein serine/threonine kinase signaling pathway (all annotations which use CV term, excluding "NOT" statements)       4     10
     involved_in | cell surface receptor protein serine/threonine kinase signaling pathway       --      10
Spanning Tree (Parents/Children)
Only view relationship: 
  cell surface receptor signaling pathway
   |__enzyme-linked receptor protein signaling pathway
       |__cell surface receptor protein serine/threonine kinase signaling pathway  94 rec.
           |__anti-Mullerian hormone receptor signaling pathway
           |   |__regulation of anti-Mullerian hormone signaling pathway(+)
           |__regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 75 rec.
           |   |__negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway(+) 46 rec.
           |   |__positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway(+) 33 rec.
           |   |__regulation of activin receptor signaling pathway(+) 7 rec.
           |   |__regulation of anti-Mullerian hormone signaling pathway(+)
           |   |__regulation of BMP signaling pathway(+) 64 rec.
           |   |__regulation of transforming growth factor beta receptor signaling pathway(+) 1 rec.
           |__SMAD protein signal transduction 11 rec.
           |   |__regulation of SMAD protein signal transduction(+) 8 rec.
           |__transforming growth factor beta receptor superfamily signaling pathway 88 rec.
               |__activin receptor signaling pathway(+) 18 rec.
               |__BMP signaling pathway(+) 76 rec.
               |__transforming growth factor beta receptor signaling pathway(+) 2 rec.
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Is a enzyme-linked receptor protein signaling pathway
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Synonyms
  • "transmembrane receptor protein serine/threonine kinase signaling pathway" BROAD
    "transmembrane receptor protein serine/threonine kinase signalling pathway" EXACT
Secondary IDs
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