FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term adenylate cyclase-modulating G protein-coupled receptor signaling pathway ID (Ontology) GO:0007188 (Gene Ontology)
Definition A G protein-coupled receptor signaling pathway in which the signal is transmitted via the activation or inhibition of adenylyl cyclase activity and a subsequent change in the intracellular concentration of cyclic AMP (cAMP).[ ISBN:0815316194 ]
Also Known As "adenylate cyclase-modulating GPCR signaling pathway" ; "G protein signaling, coupled to cAMP nucleotide second messenger" ; "G protein signaling, coupled to cyclic AMP nucleotide second messenger" (for all, see Synonyms field below)
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS      13
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 Full annotation statements 
Relevant FlyBase reports
 Genes
 adenylate cyclase-modulating G protein-coupled receptor signaling pathway (all annotations which use CV term, excluding "NOT" statements)      13
     involved_in | adenylate cyclase-modulating G protein-coupled receptor signaling pathway      13
 NOT | involved_in | adenylate cyclase-modulating G protein-coupled receptor signaling pathway       1
Spanning Tree (Parents/Children)
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  signal transduction
   |__G protein-coupled receptor signaling pathway
       |__adenylate cyclase-modulating G protein-coupled receptor signaling pathway  65 rec.
           |__adenylate cyclase-activating G protein-coupled receptor signaling pathway 44 rec.
           |   |__adenylate cyclase-activating adrenergic receptor signaling pathway(+) 8 rec.
           |   |__adenylate cyclase-activating dopamine receptor signaling pathway 4 rec.
           |   |__adenylate cyclase-activating G protein-coupled bile acid receptor signaling pathway
           |   |__adenylate cyclase-activating G protein-coupled cAMP receptor signaling pathway
           |   |__adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway
           |   |__adenylate cyclase-activating serotonin receptor signaling pathway 1 rec.
           |   |__ligand-independent adenylate cyclase-activating G protein-coupled receptor signaling pathway
           |__adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway 12 rec.
               |__adenylate cyclase-inhibiting adrenergic receptor signaling pathway
               |__adenylate cyclase-inhibiting dopamine receptor signaling pathway
               |__adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway 2 rec.
               |__adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway
               |__adenylate cyclase-inhibiting opioid receptor signaling pathway
               |__adenylate cyclase-inhibiting serotonin receptor signaling pathway 2 rec.
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Is a G protein-coupled receptor signaling pathway
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Synonyms
  • "adenylate cyclase-modulating GPCR signaling pathway" EXACT
    "G protein signaling, coupled to cAMP nucleotide second messenger" EXACT
    "G protein signaling, coupled to cyclic AMP nucleotide second messenger" EXACT
    "G protein signalling, coupled to cAMP nucleotide second messenger" EXACT
    "G protein signalling, coupled to cyclic AMP nucleotide second messenger" EXACT
    "G-protein signaling, coupled to cAMP nucleotide second messenger" EXACT
    "G-protein signaling, coupled to cyclic AMP nucleotide second messenger" EXACT
    "G-protein signalling, coupled to cAMP nucleotide second messenger" EXACT
    "G-protein signalling, coupled to cyclic AMP nucleotide second messenger" EXACT
    "GPCR signaling pathway via cAMP second messenger" EXACT
    "GPCR signaling pathway via modulation of adenylate cyclase activity" EXACT
Secondary IDs
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