FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway ID (Ontology) GO:0007193 (Gene Ontology)
Definition A G protein-coupled receptor signaling pathway in which the signal is transmitted via the inhibition of adenylyl cyclase activity and a subsequent decrease in the intracellular concentration of cyclic AMP (cAMP).[ ISBN:0815316194 ]
Also Known As "adenylate cyclase-inhibiting GPCR signaling pathway" ; "G protein signaling, adenylate cyclase inhibiting pathway" ; "G protein signaling, adenylyl cyclase inhibiting pathway" (for all, see Synonyms field below)
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Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS       8
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 Genes
 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway (all annotations which use CV term, excluding "NOT" statements)       8
     involved_in | adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway       8
Spanning Tree (Parents/Children)
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  G protein-coupled receptor signaling pathway
   |__adenylate cyclase-modulating G protein-coupled receptor signaling pathway
       |__adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway  12 rec.
           |__adenylate cyclase-inhibiting adrenergic receptor signaling pathway
           |__adenylate cyclase-inhibiting dopamine receptor signaling pathway
           |__adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway 2 rec.
           |__adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway
           |__adenylate cyclase-inhibiting opioid receptor signaling pathway
           |__adenylate cyclase-inhibiting serotonin receptor signaling pathway 2 rec.
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Is a adenylate cyclase-modulating G protein-coupled receptor signaling pathway
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Synonyms
  • "adenylate cyclase-inhibiting GPCR signaling pathway" EXACT
    "G protein signaling, adenylate cyclase inhibiting pathway" EXACT
    "G protein signaling, adenylyl cyclase inhibiting pathway" EXACT
    "G protein signalling, adenylate cyclase inhibiting pathway" EXACT
    "G protein signalling, adenylyl cyclase inhibiting pathway" EXACT
    "G-protein signaling, adenylate cyclase inhibiting pathway" EXACT
    "G-protein signaling, adenylyl cyclase inhibiting pathway" EXACT
    "G-protein signalling, adenylate cyclase inhibiting pathway" EXACT
    "G-protein signalling, adenylyl cyclase inhibiting pathway" EXACT
    "GPCR signaling pathway via inhibition of adenylate cyclase activity" EXACT
    "inhibition of adenylate cyclase activity by G-protein signaling pathway" RELATED
Secondary IDs
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Reactome:R-HSA-170670 "Adenylate cyclase inhibitory pathway"