FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term Wnt signaling pathway, calcium modulating pathway ID (Ontology) GO:0007223 (Gene Ontology)
Definition A type of non-canonical Wnt signaling in which Wnt binding to its receptor on the surface of a target cell leads to an increase in intracellular calcium and activation of protein kinase C (PKC).[ PubMed:11532397 PubMed:37804416 ]
Also Known As "Wnt receptor signaling pathway, calcium modulating pathway" ; "Wnt-activated signaling pathway, calcium modulating pathway"
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  Wnt signaling pathway
   |__non-canonical Wnt signaling pathway
       |__Wnt signaling pathway, calcium modulating pathway
           |__regulation of Wnt signaling pathway, calcium modulating pathway
               |__negative regulation of Wnt signaling pathway, calcium modulating pathway
               |__positive regulation of Wnt signaling pathway, calcium modulating pathway
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Is a non-canonical Wnt signaling pathway
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Synonyms
  • "frizzled-2 signaling pathway" NARROW
    "frizzled-2 signalling pathway" NARROW
    "non-canonical Wnt signaling pathway" BROAD
    "Wnt receptor signaling pathway, calcium modulating pathway" EXACT
    "Wnt-activated signaling pathway, calcium modulating pathway" EXACT
Secondary IDs
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Reactome:R-HSA-4086398 "Ca2+ pathway"