FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term patched ligand maturation ID (Ontology) GO:0007225 (Gene Ontology)
Definition The posttranslational modification of members of the Hedgehog family of signaling proteins in order for Hedgehog to exert its biological activity. These modifications include cleavage of its signal sequence, autocatalytic protein cleavage and the attachment of sterol groups.[ PubMed:15057936 ]
Also Known As "hh protein processing"
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Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS       2
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 Gene Groups Genes
 patched ligand maturation (all annotations which use CV term, excluding "NOT" statements)       1      2
     involved_in | patched ligand maturation       --       2
Spanning Tree (Parents/Children)
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hormone metabolic process_______________________
amide metabolic process_________________________|
signaling receptor ligand precursor processing__|
                                                peptide hormone processing
                                                 |__patched ligand maturation  3 rec.
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Is a peptide hormone processing
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Synonyms
  • "Hedgehog protein processing" NARROW
    "hh protein processing" EXACT
    "patched ligand processing" RELATED
Secondary IDs
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