FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
Help Close All Open All
General Information
Term nitric oxide mediated signal transduction ID (Ontology) GO:0007263 (Gene Ontology)
Definition An intracellular signaling cassette that starts with production of nitric oxide, detection by receptors/sensors for nitric oxide (such as soluble guanylyl cyclase/sGC) and ends with the activation of downstream effectors that further transmit the signal within the cell. Nitric oxide transmits its downstream effects through either cyclic GMP (cGMP)-dependent or independent mechanisms.[ PubMed:21549190 ]
Also Known As "nitric oxide signaling" ; "nitric oxide-mediated signal transduction" ; "NO mediated signal transduction" (for all, see Synonyms field below)
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
    Results list data from multiple species. Click on a button above and use the 'Filter by species' options on the resulting HitList to retrieve species-specific data.
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS       1
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Genes
 nitric oxide mediated signal transduction (all annotations which use CV term, excluding "NOT" statements)       1
     involved_in | nitric oxide mediated signal transduction       1
Spanning Tree (Parents/Children)
Only view relationship: 
  intracellular signal transduction
   |__intracellular signaling cassette
       |__nitric oxide mediated signal transduction  5 rec.
           |__nitric oxide-cGMP-mediated signaling 4 rec.
           |   |__regulation of nitric oxide-cGMP mediated signal transduction(+)
           |__regulation of nitric oxide mediated signal transduction
               |__negative regulation of nitric oxide mediated signal transduction(+)
               |__positive regulation of nitric oxide mediated signal transduction(+)
               |__regulation of nitric oxide-cGMP mediated signal transduction(+)
Spanning Tree View Settings
Parents/Children
View Depth
Show hierarchy levels: for parents, for children
hide Relationships
Is a intracellular signaling cassette
Part of
hide Synonyms & Secondary IDs
Synonyms
  • "nitric oxide signaling" EXACT
    "nitric oxide-mediated signal transduction" EXACT
    "NO mediated signal transduction" EXACT
    "NO-mediated signal transduction" EXACT
Secondary IDs
hide External Crossreferences & Linkouts