FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term small GTPase-mediated signal transduction ID (Ontology) GO:0007264 (Gene Ontology)
Definition An intracellular signaling cassette in which a small monomeric GTPase relays a signal.
Also Known As "small GTPase mediated signal transduction"
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS      42
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 small GTPase-mediated signal transduction (all annotations which use CV term, excluding "NOT" statements)       5     42
     involved_in | small GTPase-mediated signal transduction       --      42
Spanning Tree (Parents/Children)
Only view relationship: 
  intracellular signal transduction
   |__intracellular signaling cassette
       |__small GTPase-mediated signal transduction  194 rec.
           |__ARF protein signal transduction 10 rec.
           |   |__regulation of ARF protein signal transduction(+) 9 rec.
           |__Rab protein signal transduction 52 rec.
           |   |__regulation of Rab protein signal transduction 16 rec.
           |__Rac protein signal transduction 9 rec.
           |   |__regulation of Rac protein signal transduction(+) 4 rec.
           |__Ral protein signal transduction 3 rec.
           |   |__regulation of Ral protein signal transduction 1 rec.
           |__Ran protein signal transduction
           |__Rap protein signal transduction 5 rec.
           |   |__regulation of Rap protein signal transduction 1 rec.
           |__Ras protein signal transduction 49 rec.
           |   |__regulation of Ras protein signal transduction(+) 33 rec.
           |__regulation of small GTPase mediated signal transduction 96 rec.
           |   |__negative regulation of small GTPase mediated signal transduction(+) 8 rec.
           |   |__positive regulation of small GTPase mediated signal transduction(+) 43 rec.
           |   |__regulation of ARF protein signal transduction(+) 9 rec.
           |   |__regulation of Rab protein signal transduction 16 rec.
           |   |__regulation of Rac protein signal transduction(+) 4 rec.
           |   |__regulation of Ral protein signal transduction 1 rec.
           |   |__regulation of Rap protein signal transduction 1 rec.
           |   |__regulation of Ras protein signal transduction(+) 33 rec.
           |   |__regulation of Rho protein signal transduction(+) 25 rec.
           |   |__regulation of septation initiation signaling(+)
           |   |__symbiont-mediated perturbation of host small GTPase-mediated signal transduction(+)
           |__Rho protein signal transduction 41 rec.
           |   |__Cdc42 protein signal transduction(+) 1 rec.
           |   |__regulation of Rho protein signal transduction(+) 25 rec.
           |__septation initiation signaling
               |__regulation of septation initiation signaling(+)
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Is a intracellular signaling cassette
Part of
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Synonyms
  • "Ras family protein signal transduction" NARROW
    "small GTPase mediated signal transduction" EXACT
Secondary IDs
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Reactome:R-HSA-187706 "Signalling to p38 via RIT and RIN"
Reactome:R-HSA-194315 "Signaling by Rho GTPases"