FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term gastrulation ID (Ontology) GO:0007369 (Gene Ontology)
Definition A complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. The details of gastrulation vary from species to species, but usually result in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm.[ ISBN:9780878933846 ]
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Records annotated with this term OR any of its CHILD TERMS
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Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS      10
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 Full annotation statements 
Relevant FlyBase reports
 Genes
 gastrulation (all annotations which use CV term, excluding "NOT" statements)      10
     involved_in | gastrulation      10
Spanning Tree (Parents/Children)
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anatomical structure morphogenesis__
embryo development__________________|
                                    embryonic morphogenesis
                                     |__gastrulation  105 rec.
                                         |__cell migration involved in gastrulation 17 rec.
                                         |   |__cell migration involved in mesendoderm migration(+)
                                         |   |__dorsal convergence
                                         |   |__establishment of cell polarity involved in gastrulation cell migration(+) 4 rec.
                                         |   |__ingression involved in gastrulation with mouth forming second
                                         |   |__mediolateral intercalation 2 rec.
                                         |   |__mesoderm migration involved in gastrulation 11 rec.
                                         |__cell-cell adhesion involved in gastrulation
                                         |   |__cell-cell adhesion involved in mesendodermal cell migration
                                         |   |__regulation of cell-cell adhesion involved in gastrulation(+)
                                         |__convergent extension involved in gastrulation 6 rec.
                                         |   |__convergent extension involved in neural plate elongation(+)
                                         |   |__convergent extension involved in notochord morphogenesis(+)
                                         |   |__convergent extension involved in rhombomere morphogenesis(+)
                                         |   |__convergent extension involved in somitogenesis(+)
                                         |   |__dorsal convergence
                                         |   |__mediolateral intercalation 2 rec.
                                         |   |__regulation of convergent extension involved in gastrulation(+)
                                         |__epithelial cell morphogenesis involved in gastrulation 12 rec.
                                         |   |__apical constriction involved in gastrulation(+) 12 rec.
                                         |__formation of primary germ layer 31 rec.
                                         |   |__cell fate commitment involved in formation of primary germ layer(+) 17 rec.
                                         |   |__ectoderm formation(+) 3 rec.
                                         |   |__endoderm formation(+) 5 rec.
                                         |   |__mesoderm formation(+) 26 rec.
                                         |__gastrulation with mouth forming first 62 rec.
                                         |   |__gastrulation involving germ band extension(+) 62 rec.
                                         |__gastrulation with mouth forming second
                                         |   |__delamination involved in gastrulation with mouth forming second
                                         |   |__epiboly involved in gastrulation with mouth forming second(+)
                                         |   |__ingression involved in gastrulation with mouth forming second
                                         |   |__invagination involved in gastrulation with mouth forming second
                                         |   |__involution involved in gastrulation with mouth forming second
                                         |   |__primitive streak formation
                                         |__mesendoderm migration
                                         |   |__cell migration involved in mesendoderm migration(+)
                                         |__mesodermal to mesenchymal transition involved in gastrulation
                                         |__regulation of gastrulation 9 rec.
                                             |__negative regulation of gastrulation
                                             |__positive regulation of gastrulation 1 rec.
                                             |__regulation of apical constriction involved in ventral furrow formation(+) 3 rec.
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Reactome:R-HSA-9758941 "Gastrulation"
Wikipedia:Gastrulation