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| Term | blood coagulation, extrinsic pathway | ID (Ontology) | GO:0007598 (Gene Ontology) |
| Definition | A protein activation cascade that initiates blood coagulation, starting with a signal from tissue factor (TF), a cell-surface, integral-membrane protein, which converts Factor IX to IXa, and Factor IXa converts Factor X to Xa. Factor Xa then initiates the common pathway.[ PubMed:26018600 ] | ||
| Also Known As | "initiation of blood coagulation cascade, tissue factor pathway" | ||
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blood coagulation |__blood coagulation, fibrin clot formation__ protein maturation | |__protein activation cascade________________| protein activation cascade | |__blood coagulation, fibrin clot formation__| blood coagulation, extrinsic pathway |__regulation of blood coagulation, extrinsic pathway |__negative regulation of blood coagulation, extrinsic pathway |__positive regulation of blood coagulation, extrinsic pathway |
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| Is a | protein activation cascade | ||
| Part of | blood coagulation, fibrin clot formation | ||
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| Reactome:R-HSA-140834 "Extrinsic Pathway of Fibrin Clot Formation" | |||
