FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term COP9 signalosome ID (Ontology) GO:0008180 (Gene Ontology)
Definition A protein complex that catalyzes the deneddylation of proteins, including the cullin component of SCF ubiquitin E3 ligase; deneddylation increases the activity of cullin family ubiquitin ligases. The signalosome is involved in many regulatory process, including some which control development, in many species; also regulates photomorphogenesis in plants; in many species its subunits are highly similar to those of the proteasome.[ PubMed:11019806 PubMed:12186635 PubMed:14570571 ]
Also Known As "COP9 complex" ; "CSN"
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_CELLULAR_COMPONENT      11
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 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 COP9 signalosome (all annotations which use CV term, excluding "NOT" statements)       3     11
     part_of | COP9 signalosome       --      11
Spanning Tree (Parents/Children)
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  protein-containing complex
   |__nuclear protein-containing complex
       |__COP9 signalosome  14 rec.
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Is a nuclear protein-containing complex
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Synonyms
  • "COP9 complex" EXACT
    "CSN" EXACT
    "signalosome" BROAD
Secondary IDs
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