FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term regulation of G protein-coupled receptor signaling pathway ID (Ontology) GO:0008277 (Gene Ontology)
Definition Any process that modulates the frequency, rate or extent of G protein-coupled receptor signaling pathway.
Also Known As "regulation of G protein coupled receptor protein signaling pathway" ; "regulation of G protein coupled receptor protein signalling pathway" ; "regulation of G-protein coupled receptor protein signaling pathway" (for all, see Synonyms field below)
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS       7
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Genes
 regulation of G protein-coupled receptor signaling pathway (all annotations which use CV term, excluding "NOT" statements)       7
     involved_in | regulation of G protein-coupled receptor signaling pathway       7
Spanning Tree (Parents/Children)
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regulation of cell communication____
regulation of signaling_____________|
regulation of response to stimulus__|
                                    regulation of signal transduction
                                     |__regulation of G protein-coupled receptor signaling pathway  36 rec.
                                         |__cross-receptor inhibition within G protein-coupled receptor heterodimer
                                         |__negative regulation of G protein-coupled receptor signaling pathway 20 rec.
                                         |   |__desensitization of G protein-coupled receptor signaling pathway 4 rec.
                                         |   |__G protein-coupled receptor catabolic process
                                         |   |__negative regulation of adenosine receptor signaling pathway
                                         |   |__negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway(+) 2 rec.
                                         |   |__negative regulation of angiotensin-activated signaling pathway
                                         |   |__negative regulation of chemokine-mediated signaling pathway(+)
                                         |   |__negative regulation of dopamine receptor signaling pathway(+)
                                         |   |__negative regulation of octopamine or tyramine signaling pathway(+)
                                         |   |__negative regulation of opioid receptor signaling pathway(+)
                                         |   |__negative regulation of opsin-mediated signaling pathway(+) 15 rec.
                                         |   |__negative regulation of phospholipase C-activating G protein-coupled receptor signaling pathway(+) 5 rec.
                                         |   |__negative regulation of thrombin-activated receptor signaling pathway
                                         |   |__termination of G protein-coupled receptor signaling pathway
                                         |__positive regulation of G protein-coupled receptor signaling pathway 8 rec.
                                         |   |__negative regulation of inhibitory G protein-coupled receptor phosphorylation
                                         |   |__positive regulation of adenosine receptor signaling pathway
                                         |   |__positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway(+)
                                         |   |__positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway(+)
                                         |   |__positive regulation of angiotensin-activated signaling pathway
                                         |   |__positive regulation of chemokine-mediated signaling pathway(+)
                                         |   |__positive regulation of dopamine receptor signaling pathway(+)
                                         |   |__positive regulation of octopamine or tyramine signaling pathway(+) 4 rec.
                                         |   |__positive regulation of opioid receptor signaling pathway(+)
                                         |   |__positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway 2 rec.
                                         |   |__positive regulation of thrombin-activated receptor signaling pathway
                                         |__protein kinase C deactivation
                                         |__regulation of adenosine receptor signaling pathway
                                         |   |__negative regulation of adenosine receptor signaling pathway
                                         |   |__positive regulation of adenosine receptor signaling pathway
                                         |__regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway 2 rec.
                                         |   |__negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway(+) 2 rec.
                                         |   |__positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway(+)
                                         |   |__regulation of adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway(+)
                                         |__regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway
                                         |__regulation of angiotensin-activated signaling pathway
                                         |   |__negative regulation of angiotensin-activated signaling pathway
                                         |   |__positive regulation of angiotensin-activated signaling pathway
                                         |__regulation of chemokine-mediated signaling pathway
                                         |   |__negative regulation of chemokine-mediated signaling pathway(+)
                                         |   |__positive regulation of chemokine-mediated signaling pathway(+)
                                         |   |__regulation of C-C chemokine receptor CCR7 signaling pathway(+)
                                         |__regulation of dopamine receptor signaling pathway 1 rec.
                                         |   |__negative regulation of dopamine receptor signaling pathway(+)
                                         |   |__positive regulation of dopamine receptor signaling pathway(+)
                                         |   |__regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway(+)
                                         |__regulation of endocannabinoid signaling pathway
                                         |__regulation of G protein-coupled receptor internalization
                                         |   |__negative regulation of G protein-coupled receptor internalization
                                         |   |__positive regulation of G protein-coupled receptor internalization
                                         |__regulation of octopamine or tyramine signaling pathway 4 rec.
                                         |   |__negative regulation of octopamine or tyramine signaling pathway(+)
                                         |   |__positive regulation of octopamine or tyramine signaling pathway(+) 4 rec.
                                         |   |__regulation of octopamine signaling pathway(+) 4 rec.
                                         |   |__regulation of tyramine signaling pathway(+)
                                         |__regulation of opioid receptor signaling pathway
                                         |   |__negative regulation of opioid receptor signaling pathway(+)
                                         |   |__positive regulation of opioid receptor signaling pathway(+)
                                         |   |__regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway(+)
                                         |__regulation of opsin-mediated signaling pathway 15 rec.
                                         |   |__negative regulation of opsin-mediated signaling pathway(+) 15 rec.
                                         |__regulation of phospholipase C-activating G protein-coupled receptor signaling pathway 7 rec.
                                         |   |__negative regulation of phospholipase C-activating G protein-coupled receptor signaling pathway(+) 5 rec.
                                         |   |__positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway 2 rec.
                                         |__regulation of thrombin-activated receptor signaling pathway
                                             |__negative regulation of thrombin-activated receptor signaling pathway
                                             |__positive regulation of thrombin-activated receptor signaling pathway
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Is a regulation of signal transduction
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Synonyms
  • "regulation of G protein coupled receptor protein signaling pathway" EXACT
    "regulation of G protein coupled receptor protein signalling pathway" EXACT
    "regulation of G-protein coupled receptor protein signaling pathway" EXACT
    "regulation of G-protein coupled receptor protein signalling pathway" EXACT
    "regulation of G-protein-coupled receptor protein signalling pathway" EXACT
    "regulation of GPCR protein signaling pathway" EXACT
    "regulation of GPCR protein signalling pathway" EXACT
Secondary IDs
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