FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term fibroblast growth factor receptor signaling pathway ID (Ontology) GO:0008543 (Gene Ontology)
Definition The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands.
Also Known As "FGF receptor signaling pathway" ; "FGF receptor signalling pathway" ; "FGFR signaling pathway" (for all, see Synonyms field below)
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS      25
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 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 fibroblast growth factor receptor signaling pathway (all annotations which use CV term, excluding "NOT" statements)       2     25
     acts_upstream_of_positive_effect | fibroblast growth factor receptor signaling pathway       --       2
     involved_in | fibroblast growth factor receptor signaling pathway       --      23
Spanning Tree (Parents/Children)
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  enzyme-linked receptor protein signaling pathway
   |__cell surface receptor protein tyrosine kinase signaling pathway
       |__fibroblast growth factor receptor signaling pathway  43 rec.
           |__fibroblast growth factor receptor apoptotic signaling pathway
           |__fibroblast growth factor receptor signaling pathway involved in forebrain neuroblast division
           |__fibroblast growth factor receptor signaling pathway involved in forebrain neuron fate commitment
           |__fibroblast growth factor receptor signaling pathway involved in heart development
           |__fibroblast growth factor receptor signaling pathway involved in hemopoiesis
           |__fibroblast growth factor receptor signaling pathway involved in mammary gland specification
           |__fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell
           |__fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation
           |   |__negative regulation of anterior neural cell fate commitment of the neural plate by fibroblast growth factor receptor signaling pathway
           |__fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development
           |__fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow
           |__fibroblast growth factor receptor signaling pathway involved in somitogenesis
           |__fibroblast growth factor receptor signaling pathway involved in spinal cord anterior/posterior pattern formation
           |__fibroblast growth factor receptor signaling pathway involved in ureteric bud formation
           |__positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway
           |__positive regulation of posterior neural plate formation by fibroblast growth factor receptor signaling pathway
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Is a cell surface receptor protein tyrosine kinase signaling pathway
Part of cellular response to fibroblast growth factor stimulus
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Synonyms
  • "FGF receptor signaling pathway" EXACT
    "FGF receptor signalling pathway" EXACT
    "FGFR signaling pathway" EXACT
    "fibroblast growth factor receptor signalling pathway" EXACT
Secondary IDs
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Reactome:R-HSA-190236 "Signaling by FGFR"