FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term regulation of smoothened signaling pathway ID (Ontology) GO:0008589 (Gene Ontology)
Definition Any process that modulates the frequency, rate or extent of smoothened signaling.
Also Known As "regulation of hedgehog signaling pathway" ; "regulation of hh signaling pathway" ; "regulation of smoothened signalling pathway"
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Annotations
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS       1
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 Full annotation statements 
Relevant FlyBase reports
 Genes
 regulation of smoothened signaling pathway (all annotations which use CV term, excluding "NOT" statements)       1
     involved_in | regulation of smoothened signaling pathway       1
Spanning Tree (Parents/Children)
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signal transduction
 |__regulation of signal transduction____
cell surface receptor signaling pathway  |
 |__smoothened signaling pathway_________|
regulation of cell communication         |
 |__regulation of signal transduction____|
regulation of signaling                  |
 |__regulation of signal transduction____|
regulation of response to stimulus       |
 |__regulation of signal transduction____|
                                         regulation of smoothened signaling pathway  96 rec.
                                          |__negative regulation of smoothened signaling pathway 60 rec.
                                          |   |__negative regulation of hh target transcription factor activity
                                          |   |__negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                          |   |__negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning
                                          |__positive regulation of smoothened signaling pathway 46 rec.
                                          |   |__positive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                          |__regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                              |__negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                              |__positive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
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Is a regulation of signal transduction
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Synonyms
  • "regulation of hedgehog signaling pathway" EXACT
    "regulation of hh signaling pathway" EXACT
    "regulation of smoothened activity" RELATED
    "regulation of smoothened by patched" RELATED
    "regulation of smoothened receptor activity by patched" RELATED
    "regulation of smoothened signalling pathway" EXACT
Secondary IDs
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