FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term peptidyl-lysine modification to peptidyl-hypusine ID (Ontology) GO:0008612 (Gene Ontology)
Definition The modification of peptidyl-lysine to form hypusine, peptidyl-N6-(4-amino-2-hydroxybutyl)-L-lysine.[ ISBN:0198547684 ]
Also Known As "hypusine anabolism" ; "hypusine anabolism from peptidyl-lysine" ; "hypusine biosynthesis" (for all, see Synonyms field below)
Comment
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS       1
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 Full annotation statements 
Relevant FlyBase reports
 Genes
 peptidyl-lysine modification to peptidyl-hypusine (all annotations which use CV term, excluding "NOT" statements)       1
     involved_in | peptidyl-lysine modification to peptidyl-hypusine       1
Spanning Tree (Parents/Children)
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metabolic process
 |__biosynthetic process__________
peptidyl-amino acid modification  |
 |__peptidyl-lysine modification__|
protein metabolic process         |
 |__protein maturation____________|
                                  peptidyl-lysine modification to peptidyl-hypusine  1 rec.
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Is a biosynthetic process
peptidyl-lysine modification
protein maturation
Part of
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Synonyms
  • "hypusine anabolism" EXACT
    "hypusine anabolism from peptidyl-lysine" EXACT
    "hypusine biosynthesis" EXACT
    "hypusine biosynthetic process" EXACT
    "hypusine biosynthetic process from peptidyl-lysine" EXACT
    "hypusine formation" EXACT
    "hypusine formation from peptidyl-lysine" EXACT
    "hypusine synthesis" EXACT
    "hypusine synthesis from peptidyl-lysine" EXACT
    "hypusinylation" EXACT
    "protein hypusination" EXACT
Secondary IDs
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Reactome:R-HSA-204626 "Hypusine synthesis from eIF5A-lysine"
RESID:AA0116