FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term tRNA queuosine(34) biosynthetic process ID (Ontology) GO:0008616 (Gene Ontology)
Definition The chemical reactions and pathways resulting in the formation of queuosines, a series of nucleosides found in position 34 of tRNA and having an additional pentenyl ring added via an NH group to the methyl group of 7-methylguanosine. The pentenyl ring may carry other substituents. The wobble nucleoside of the tRNA sequence (position 34) corresponds to the first position of the anticodon.[ PubMed:28208705 PubMed:39600051 ]
Also Known As "queuosine anabolism" ; "queuosine biosynthesis" ; "queuosine biosynthetic process" (for all, see Synonyms field below)
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tRNA wobble base modification
 |__tRNA wobble guanine modification__
metabolic process                     |
 |__biosynthetic process______________|
                                      tRNA queuosine(34) biosynthetic process
                                       |__de novo tRNA queuosine(34) biosynthetic process
                                       |__tRNA queuosine(34) biosynthetic process from salvaged queuine
                                       |__tRNA queuosine(34) biosynthetic process from salvaged queuosine or its precursors
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Is a tRNA wobble guanine modification
biosynthetic process
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Synonyms
  • "queuosine anabolism" EXACT
    "queuosine biosynthesis" EXACT
    "queuosine biosynthetic process" EXACT
    "queuosine formation" EXACT
    "queuosine synthesis" EXACT
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