General Information
Term	extrinsic apoptotic signaling pathway via death domain receptors	ID (Ontology)	GO:0008625 (Gene Ontology)
Definition	The series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with a ligand binding to a death domain receptor on the cell surface, and ends when the execution phase of apoptosis is triggered.
Also Known As	"induction of apoptosis via death receptors"
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General Information

Term

extrinsic apoptotic signaling pathway via death domain receptors

ID (Ontology)

GO:0008625 (Gene Ontology)

Definition

The series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with a ligand binding to a death domain receptor on the cell surface, and ends when the execution phase of apoptosis is triggered.

Also Known As

"induction of apoptosis via death receptors"

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

No relevant statements available

cell surface receptor signaling pathway__
apoptotic signaling pathway______________|
                                         extrinsic apoptotic signaling pathway
                                          |__extrinsic apoptotic signaling pathway via death domain receptors  3 rec.
                                              |__regulation of extrinsic apoptotic signaling pathway via death domain receptors 3 rec.
                                              |   |__negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(+) 2 rec.
                                              |   |__positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(+)
                                              |   |__regulation of TRAIL-activated apoptotic signaling pathway(+)
                                              |__TRAIL-activated apoptotic signaling pathway
                                                  |__regulation of TRAIL-activated apoptotic signaling pathway(+)
                                                  |__TRAIL death-inducing signaling complex assembly

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Is a	extrinsic apoptotic signaling pathway
Part of
Synonyms & Secondary IDs
Synonyms
	"death receptor-mediated apoptosis" NARROW "induction of apoptosis via death domain receptors" RELATED "induction of apoptosis via death receptors" EXACT
Secondary IDs

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Is a

extrinsic apoptotic signaling pathway

Part of

Synonyms & Secondary IDs

Synonyms

"death receptor-mediated apoptosis" NARROW
"induction of apoptosis via death domain receptors" RELATED
"induction of apoptosis via death receptors" EXACT

Secondary IDs

External Crossreferences & Linkouts