FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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Term granzyme-mediated apoptotic signaling pathway ID (Ontology) GO:0008626 (Gene Ontology)
Definition The series of molecular signals induced by granzymes which triggers the apoptotic death of a cell. The pathway starts with reception of a granzyme signal, and ends when the execution phase of apoptosis is triggered. Granzymes are serine proteases that are secreted by cytotoxic T cells and natural killer cells to induce apoptosis in target cells.[ PubMed:17158907 ]
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apoptotic process
 |__apoptotic signaling pathway________________________________
signal transduction                                            |
 |__apoptotic signaling pathway________________________________|
 |__granzyme-mediated programmed cell death signaling pathway__|
programmed cell death                                          |
 |__granzyme-mediated programmed cell death signaling pathway__|
                                                               granzyme-mediated apoptotic signaling pathway
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Is a apoptotic signaling pathway
granzyme-mediated programmed cell death signaling pathway
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Synonyms
  • "apoptotic signaling pathway in response to granzyme" RELATED
    "induction of apoptosis by granzyme" RELATED
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