FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term negative regulation of biosynthetic process ID (Ontology) GO:0009890 (Gene Ontology)
Definition Any process that stops, prevents, or reduces the rate of the chemical reactions and pathways resulting in the formation of substances.
Also Known As "down regulation of biosynthetic process" ; "down-regulation of biosynthetic process" ; "downregulation of biosynthetic process" (for all, see Synonyms field below)
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Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS       2
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 Genes
 negative regulation of biosynthetic process (all annotations which use CV term, excluding "NOT" statements)       2
     involved_in | negative regulation of biosynthetic process       2
Spanning Tree (Parents/Children)
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biosynthetic process
 |__regulation of biosynthetic process________
regulation of metabolic process               |
 |__regulation of biosynthetic process________|
 |__negative regulation of metabolic process__|
negative regulation of cellular process       |
 |__negative regulation of metabolic process__|
                                              negative regulation of biosynthetic process  943 rec.
                                               |__negative regulation of (R)-mevalonic acid biosynthetic process
                                               |__negative regulation of acetylcholine biosynthetic process
                                               |__negative regulation of alcohol biosynthetic process
                                               |   |__negative regulation of abscisic acid biosynthetic process
                                               |   |__negative regulation of aldosterone biosynthetic process
                                               |   |__negative regulation of asperfuranone biosynthetic process
                                               |   |__negative regulation of butyryl-CoA catabolic process to butanol
                                               |   |__negative regulation of cholesterol biosynthetic process
                                               |   |__negative regulation of cortisol biosynthetic process
                                               |   |__negative regulation of ergosterol biosynthetic process
                                               |   |__negative regulation of inositol biosynthetic process
                                               |   |__negative regulation of inositol phosphate biosynthetic process(+)
                                               |   |__negative regulation of kojic acid biosynthetic process
                                               |   |__negative regulation of neosartoricin biosynthetic process
                                               |   |__negative regulation of thiamine biosynthetic process
                                               |__negative regulation of alkane biosynthetic process
                                               |   |__negative regulation of heptadecane biosynthetic process
                                               |   |__negative regulation of methane biosynthetic process from 3-(methylthio)propionic acid
                                               |   |__negative regulation of methane biosynthetic process from carbon monoxide
                                               |   |__negative regulation of methane biosynthetic process from dimethyl sulfide
                                               |   |__negative regulation of methane biosynthetic process from dimethylamine
                                               |   |__negative regulation of methane biosynthetic process from formic acid
                                               |   |__negative regulation of methane biosynthetic process from methanethiol
                                               |   |__negative regulation of methane biosynthetic process from methylamine
                                               |   |__negative regulation of methane biosynthetic process from trimethylamine
                                               |   |__negative regulation of pentadecane biosynthetic process
                                               |   |__negative regulation of tridecane biosynthetic process
                                               |__negative regulation of amino acid biosynthetic process
                                               |   |__negative regulation of citrulline biosynthetic process
                                               |   |__negative regulation of histidine biosynthetic process
                                               |   |__negative regulation of homoserine biosynthetic process
                                               |   |__negative regulation of L-dopa biosynthetic process
                                               |   |__negative regulation of L-glutamine biosynthetic process
                                               |   |__negative regulation of L-leucine biosynthetic process
                                               |   |__negative regulation of L-proline biosynthetic process
                                               |   |__negative regulation of lysine biosynthetic process via aminoadipic acid(+)
                                               |__negative regulation of austinol biosynthetic process
                                               |__negative regulation of collagen biosynthetic process
                                               |__negative regulation of dopamine biosynthetic process
                                               |__negative regulation of flavonoid biosynthetic process
                                               |   |__negative regulation of anthocyanin biosynthetic process
                                               |   |__negative regulation of flavonol biosynthetic process
                                               |__negative regulation of fumagillin biosynthetic process
                                               |__negative regulation of gluconeogenesis
                                               |__negative regulation of glutathione biosynthetic process
                                               |__negative regulation of hexadecanal biosynthetic process
                                               |__negative regulation of hormone biosynthetic process 4 rec.
                                               |   |__negative regulation of androgen biosynthetic process
                                               |   |__negative regulation of estrogen biosynthetic process
                                               |   |__negative regulation of indoleacetic acid biosynthetic process via tryptophan
                                               |   |__negative regulation of juvenile hormone biosynthetic process 3 rec.
                                               |   |__negative regulation of progesterone biosynthetic process(+)
                                               |   |__negative regulation of steroid hormone biosynthetic process(+)
                                               |__negative regulation of hydrogen sulfide biosynthetic process
                                               |__negative regulation of L-ascorbic acid biosynthetic process
                                               |__negative regulation of lactose biosynthetic process
                                               |__negative regulation of lipid biosynthetic process 6 rec.
                                               |   |__negative regulation of abscisic acid biosynthetic process
                                               |   |__negative regulation of butyryl-CoA catabolic process to butanol
                                               |   |__negative regulation of carotenoid biosynthetic process
                                               |   |__negative regulation of diacylglycerol biosynthetic process
                                               |   |__negative regulation of emericellamide biosynthetic process(+)
                                               |   |__negative regulation of ent-pimara-8(14),15-diene biosynthetic process
                                               |   |__negative regulation of fatty acid biosynthetic process(+) 2 rec.
                                               |   |__negative regulation of gibberellin biosynthetic process
                                               |   |__negative regulation of isoprene biosynthetic process
                                               |   |__negative regulation of juvenile hormone biosynthetic process 3 rec.
                                               |   |__negative regulation of phospholipid biosynthetic process(+)
                                               |   |__negative regulation of retinoic acid biosynthetic process
                                               |   |__negative regulation of sphingolipid biosynthetic process(+)
                                               |   |__negative regulation of steroid biosynthetic process(+)
                                               |   |__negative regulation of triglyceride biosynthetic process 1 rec.
                                               |   |__negative regulation of wax biosynthetic process
                                               |__negative regulation of macromolecule biosynthetic process 929 rec.
                                               |   |__negative regulation of (1->3)-beta-D-glucan biosynthetic process
                                               |   |__negative regulation of cellulose biosynthetic process(+)
                                               |   |__negative regulation of cutin biosynthetic process
                                               |   |__negative regulation of DNA biosynthetic process(+)
                                               |   |__negative regulation of gene expression(+) 660 rec.
                                               |   |__negative regulation of glycogen biosynthetic process 1 rec.
                                               |   |__negative regulation of glycoprotein biosynthetic process(+) 1 rec.
                                               |   |__negative regulation of hemoglobin biosynthetic process
                                               |   |__negative regulation of hyaluronan biosynthetic process
                                               |   |__negative regulation of integrin biosynthetic process(+)
                                               |   |__negative regulation of MHC class I biosynthetic process
                                               |   |__negative regulation of MHC class II biosynthetic process
                                               |   |__negative regulation of protein lipidation(+)
                                               |   |__negative regulation of RNA biosynthetic process(+) 322 rec.
                                               |   |__negative regulation of starch biosynthetic process
                                               |__negative regulation of methanofuran biosynthetic process
                                               |__negative regulation of methanophenazine biosynthetic process
                                               |__negative regulation of naphtho-gamma-pyrone biosynthetic process
                                               |__negative regulation of nitric oxide biosynthetic process
                                               |__negative regulation of nucleotide biosynthetic process
                                               |   |__negative regulation of purine nucleotide biosynthetic process(+)
                                               |   |__negative regulation of pyrimidine nucleotide biosynthetic process(+)
                                               |__negative regulation of olefin biosynthetic process
                                               |   |__negative regulation of (Z)-nonadeca-1,14-diene biosynthetic process
                                               |   |__negative regulation of 17-methylnonadec-1-ene biosynthetic process
                                               |   |__negative regulation of 18-methylnonadec-1-ene biosynthetic process
                                               |   |__negative regulation of ethylene biosynthetic process
                                               |   |__negative regulation of isoprene biosynthetic process
                                               |   |__negative regulation of nonadec-1-ene biosynthetic process
                                               |   |__negative regulation of octadecene biosynthetic process
                                               |__negative regulation of phenazine biosynthetic process
                                               |__negative regulation of polyamine biosynthetic process
                                               |   |__negative regulation of spermidine biosynthetic process
                                               |__negative regulation of pseurotin A biosynthetic process
                                               |__negative regulation of pyruvate decarboxylation to acetyl-CoA
                                               |__negative regulation of quinolinate biosynthetic process
                                               |__negative regulation of raffinose biosynthetic process
                                               |__negative regulation of reactive oxygen species biosynthetic process 3 rec.
                                               |   |__negative regulation of hydrogen peroxide biosynthetic process
                                               |__negative regulation of reductive pentose-phosphate cycle
                                               |__negative regulation of sarcinapterin biosynthetic process
                                               |__negative regulation of secondary metabolite biosynthetic process 1 rec.
                                               |   |__negative regulation of (+)-kotanin biosynthetic process
                                               |   |__negative regulation of aflatoxin biosynthetic process
                                               |   |__negative regulation of arugosin biosynthetic process
                                               |   |__negative regulation of asperthecin biosynthetic process
                                               |   |__negative regulation of cordyol C biosynthetic process
                                               |   |__negative regulation of dehydroaustinol biosynthetic process
                                               |   |__negative regulation of demethylkotanin biosynthetic process
                                               |   |__negative regulation of diorcinol biosynthetic process
                                               |   |__negative regulation of emericellamide biosynthetic process(+)
                                               |   |__negative regulation of emericellin biosynthetic process
                                               |   |__negative regulation of emodin biosynthetic process
                                               |   |__negative regulation of endocrocin biosynthetic process
                                               |   |__negative regulation of ergot alkaloid biosynthetic process(+)
                                               |   |__negative regulation of fumonisin biosynthetic process
                                               |   |__negative regulation of gerfelin biosynthetic process
                                               |   |__negative regulation of gliotoxin biosynthetic process
                                               |   |__negative regulation of helvolic acid biosynthetic process
                                               |   |__negative regulation of melanin biosynthetic process 1 rec.
                                               |   |__negative regulation of monodictyphenone biosynthetic process
                                               |   |__negative regulation of N',N'',N'''-triacetylfusarinine C biosynthetic process
                                               |   |__negative regulation of o-orsellinic acid biosynthetic process
                                               |   |__negative regulation of orcinol biosynthetic process
                                               |   |__negative regulation of penicillin biosynthetic process
                                               |   |__negative regulation of polyketide biosynthetic process(+)
                                               |   |__negative regulation of siderophore biosynthetic process(+)
                                               |   |__negative regulation of sinapate ester biosynthetic process
                                               |   |__negative regulation of sterigmatocystin biosynthetic process
                                               |   |__negative regulation of syringal lignin biosynthetic process
                                               |   |__negative regulation of tensidol A biosynthetic process
                                               |   |__negative regulation of tensidol B biosynthetic process
                                               |   |__negative regulation of violaceol I biosynthetic process
                                               |   |__negative regulation of violaceol II biosynthetic process
                                               |__negative regulation of serotonin biosynthetic process
                                               |__negative regulation of tatiopterin biosynthetic process
                                               |__negative regulation of tetrapyrrole biosynthetic process
                                               |   |__negative regulation of chlorophyll biosynthetic process
                                               |   |__negative regulation of heme biosynthetic process
                                               |   |__negative regulation of tetrapyrrole biosynthetic process from glutamate
                                               |   |__negative regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA
                                               |__negative regulation of thiamine diphosphate biosynthetic process
                                               |__negative regulation of trypanothione biosynthetic process
                                               |__negative regulation of ubiquinone biosynthetic process
                                               |__negative regulation of UDP-N-acetylglucosamine biosynthetic process 1 rec.
                                               |__negative regulation of xanthone-containing compound biosynthetic process
                                                   |__negative regulation of emericellin biosynthetic process
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Is a regulation of biosynthetic process
negative regulation of metabolic process
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Synonyms
  • "down regulation of biosynthetic process" EXACT
    "down-regulation of biosynthetic process" EXACT
    "downregulation of biosynthetic process" EXACT
    "inhibition of biosynthetic process" NARROW
    "negative regulation of anabolism" EXACT
    "negative regulation of biosynthesis" EXACT
    "negative regulation of formation" EXACT
    "negative regulation of synthesis" EXACT
Secondary IDs
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