FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term regulation of pyruvate decarboxylation to acetyl-CoA ID (Ontology) GO:0010510 (Gene Ontology)
Definition Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of acetyl-CoA from pyruvate. In most organisms, this pathway links glycolysis to the TCA cycle, by a series of three reactions carried out by a multisubunit complex called the 'pyruvate dehydrogenase complex', even though pyruvate dehydrogenase activity describes only one of those reactions.
Also Known As "regulation of acetyl-CoA biosynthetic process from pyruvate"
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Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS       1
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 Genes
 regulation of pyruvate decarboxylation to acetyl-CoA (all annotations which use CV term, excluding "NOT" statements)       1
     involved_in | regulation of pyruvate decarboxylation to acetyl-CoA       1
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regulation of biosynthetic process______________________________
regulation of fatty acid metabolic process______________________|
regulation of nucleobase-containing compound metabolic process__|
regulation of amide metabolic process___________________________|
regulation of sulfur metabolic process__________________________|
regulation of phosphorus metabolic process______________________|
                                                                regulation of acyl-CoA biosynthetic process
                                                                 |__regulation of pyruvate decarboxylation to acetyl-CoA  3 rec.
                                                                     |__negative regulation of pyruvate decarboxylation to acetyl-CoA
                                                                     |__positive regulation of pyruvate decarboxylation to acetyl-CoA 2 rec.
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Is a regulation of acyl-CoA biosynthetic process
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Synonyms
  • "regulation of acetyl-CoA biosynthetic process from pyruvate" EXACT
Secondary IDs
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Reactome:R-HSA-204174 "Regulation of pyruvate dehydrogenase (PDH) complex"