FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term positive regulation of gene expression ID (Ontology) GO:0010628 (Gene Ontology)
Definition Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA).
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS      75
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Genes
 positive regulation of gene expression (all annotations which use CV term, excluding "NOT" statements)      75
     acts_upstream_of | positive regulation of gene expression       4
     involved_in | positive regulation of gene expression      72
Spanning Tree (Parents/Children)
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positive regulation of biosynthetic process
 |__positive regulation of macromolecule biosynthetic process__
regulation of macromolecule biosynthetic process               |
 |__regulation of gene expression______________________________|
 |__positive regulation of macromolecule biosynthetic process__|
positive regulation of macromolecule metabolic process         |
 |__positive regulation of macromolecule biosynthetic process__|
                                                               positive regulation of gene expression  224 rec.
                                                                |__negative regulation of gene silencing by regulatory ncRNA 10 rec.
                                                                |   |__negative regulation of post-transcriptional gene silencing by regulatory ncRNA(+) 9 rec.
                                                                |   |__negative regulation of regulatory ncRNA-mediated heterochromatin formation 1 rec.
                                                                |__negative regulation of heterochromatin formation 9 rec.
                                                                |   |__negative regulation of DNA methylation-dependent heterochromatin formation
                                                                |   |__negative regulation of rDNA heterochromatin formation
                                                                |   |__negative regulation of regulatory ncRNA-mediated heterochromatin formation 1 rec.
                                                                |   |__negative regulation of silent mating-type cassette heterochromatin formation
                                                                |__negative regulation of mRNA catabolic process 11 rec.
                                                                |   |__mRNA stabilization(+) 9 rec.
                                                                |   |__negative regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA
                                                                |   |__negative regulation of mitochondrial mRNA catabolic process 2 rec.
                                                                |   |__negative regulation of nuclear mRNA surveillance of meiosis-specific transcripts
                                                                |   |__negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(+)
                                                                |   |__negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
                                                                |__negative regulation of post-transcriptional gene silencing 9 rec.
                                                                |   |__negative regulation of post-transcriptional gene silencing by regulatory ncRNA(+) 9 rec.
                                                                |__positive regulation of 3'-UTR-mediated mRNA stabilization 1 rec.
                                                                |__positive regulation of cytokine production 3 rec.
                                                                |   |__positive regulation of amphiregulin production
                                                                |   |__positive regulation of chemokine production(+)
                                                                |   |__positive regulation of connective tissue growth factor production
                                                                |   |__positive regulation of cytokine production involved in immune response(+)
                                                                |   |__positive regulation of cytokine production involved in inflammatory response
                                                                |   |__positive regulation of endothelin production
                                                                |   |__positive regulation of fibroblast growth factor production
                                                                |   |__positive regulation of glial cell-derived neurotrophic factor production
                                                                |   |__positive regulation of granulocyte macrophage colony-stimulating factor production
                                                                |   |__positive regulation of hepatocyte growth factor production
                                                                |   |__positive regulation of interleukin-1 production(+)
                                                                |   |__positive regulation of interleukin-2 production
                                                                |   |__positive regulation of interleukin-3 production
                                                                |   |__positive regulation of interleukin-4 production
                                                                |   |__positive regulation of interleukin-5 production
                                                                |   |__positive regulation of interleukin-6 production
                                                                |   |__positive regulation of interleukin-7 production
                                                                |   |__positive regulation of interleukin-8 production
                                                                |   |__positive regulation of interleukin-9 production
                                                                |   |__positive regulation of interleukin-10 production
                                                                |   |__positive regulation of interleukin-11 production
                                                                |   |__positive regulation of interleukin-12 production
                                                                |   |__positive regulation of interleukin-13 production
                                                                |   |__positive regulation of interleukin-15 production
                                                                |   |__positive regulation of interleukin-16 production
                                                                |   |__positive regulation of interleukin-17 production(+)
                                                                |   |__positive regulation of interleukin-18 production
                                                                |   |__positive regulation of interleukin-19 production
                                                                |   |__positive regulation of interleukin-20 production
                                                                |   |__positive regulation of interleukin-21 production
                                                                |   |__positive regulation of interleukin-22 production
                                                                |   |__positive regulation of interleukin-23 production
                                                                |   |__positive regulation of interleukin-24 production
                                                                |   |__positive regulation of interleukin-25 production
                                                                |   |__positive regulation of interleukin-26 production
                                                                |   |__positive regulation of interleukin-27 production
                                                                |   |__positive regulation of interleukin-32 production
                                                                |   |__positive regulation of interleukin-33 production
                                                                |   |__positive regulation of interleukin-34 production
                                                                |   |__positive regulation of interleukin-35 production
                                                                |   |__positive regulation of interleukin-37 production
                                                                |   |__positive regulation of macrophage colony-stimulating factor production(+)
                                                                |   |__positive regulation of platelet-derived growth factor production
                                                                |   |__positive regulation of transforming growth factor beta production(+)
                                                                |   |__positive regulation of tumor necrosis factor superfamily cytokine production(+)
                                                                |   |__positive regulation of type I interferon production(+) 2 rec.
                                                                |   |__positive regulation of type II interferon production
                                                                |   |__positive regulation of type III interferon production
                                                                |   |__positive regulation of vascular endothelial growth factor production 1 rec.
                                                                |__positive regulation of gene expression, epigenetic 14 rec.
                                                                |   |__chromosomal 5-methylcytosine DNA demethylation, oxidation pathway
                                                                |   |__transcription initiation-coupled chromatin remodeling(+) 13 rec.
                                                                |__positive regulation of miRNA processing
                                                                |   |__positive regulation of pre-miRNA processing
                                                                |   |__positive regulation of primary miRNA processing
                                                                |__positive regulation of oxytocin production
                                                                |__positive regulation of production of molecular mediator of immune response 61 rec.
                                                                |   |__positive regulation of antimicrobial peptide production(+) 61 rec.
                                                                |   |__positive regulation of cytokine production involved in immune response(+)
                                                                |   |__positive regulation of granzyme A production
                                                                |   |__positive regulation of granzyme B production
                                                                |   |__positive regulation of immunoglobulin production(+)
                                                                |__positive regulation of protein maturation 2 rec.
                                                                |   |__positive regulation of N-terminal peptidyl-lysine acetylation
                                                                |   |__positive regulation of N-terminal peptidyl-methionine acetylation
                                                                |   |__positive regulation of protein activation cascade(+)
                                                                |   |__positive regulation of protein processing(+) 2 rec.
                                                                |__positive regulation of RNA splicing 6 rec.
                                                                |   |__positive regulation of mRNA splicing, via spliceosome(+) 3 rec.
                                                                |__positive regulation of snoRNA processing
                                                                |__positive regulation of translation 47 rec.
                                                                |   |__positive regulation of cytoplasmic translation 5 rec.
                                                                |   |__positive regulation of mitochondrial translation(+) 5 rec.
                                                                |   |__positive regulation of oskar mRNA translation 5 rec.
                                                                |   |__positive regulation of translation in response to stress(+)
                                                                |   |__positive regulation of translation, ncRNA-mediated
                                                                |   |__positive regulation of translational elongation(+) 1 rec.
                                                                |   |__positive regulation of translational fidelity
                                                                |   |__positive regulation of translational initiation(+) 5 rec.
                                                                |   |__positive regulation of translational termination 2 rec.
                                                                |__positive regulation of tRNA processing 1 rec.
                                                                |   |__positive regulation of tRNA methylation(+)
                                                                |__transcription antitermination
                                                                |__zygotic genome activation
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positive regulation of macromolecule biosynthetic process
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