FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
Help Close All Open All
General Information
Term muscle hypertrophy ID (Ontology) GO:0014896 (Gene Ontology)
Definition The muscle system process that results in enlargement or overgrowth of all or part of a muscle organ due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development (it stops in cardiac muscle after adolescence) and can also be brought on in response to demand. In athletes cardiac and skeletal muscles undergo hypertrophy stimulated by increasing muscle activity on exercise. Smooth muscle cells in the uterus undergo hypertrophy during pregnancy.
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
    Results list data from multiple species. Click on a button above and use the 'Filter by species' options on the resulting HitList to retrieve species-specific data.
Records annotated with this exact term (annotations to child terms are NOT included)
No relevant records available
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
No relevant statements available
Spanning Tree (Parents/Children)
Only view relationship:
  system process
   |__muscle system process
       |__muscle hypertrophy  2 rec.
           |__muscle hypertrophy in response to stress
           |   |__cardiac muscle hypertrophy in response to stress(+)
           |__physiological muscle hypertrophy
           |   |__physiological cardiac muscle hypertrophy(+)
           |__regulation of muscle hypertrophy 2 rec.
           |   |__negative regulation of muscle hypertrophy(+)
           |   |__positive regulation of muscle hypertrophy(+)
           |   |__regulation of cardiac muscle hypertrophy(+)
           |   |__regulation of myofibril size 2 rec.
           |   |__regulation of skeletal muscle hypertrophy(+)
           |   |__regulation of smooth muscle hypertrophy(+)
           |__smooth muscle hypertrophy
           |   |__regulation of smooth muscle hypertrophy(+)
           |__striated muscle hypertrophy
               |__cardiac muscle hypertrophy(+)
               |__skeletal muscle hypertrophy(+)
Spanning Tree View Settings
Parents/Children
View Depth
Show hierarchy levels: for parents, for children
hide Relationships
Is a muscle system process
Part of
hide Synonyms & Secondary IDs
Synonyms
Secondary IDs
hide External Crossreferences & Linkouts
Wikipedia:Muscle_hypertrophy