FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term dystrophin-associated glycoprotein complex ID (Ontology) GO:0016010 (Gene Ontology)
Definition A multiprotein complex that forms a strong mechanical link between the cytoskeleton and extracellular matrix; typical of, but not confined to, muscle cells. The complex is composed of transmembrane, cytoplasmic, and extracellular proteins, including dystrophin, sarcoglycans, dystroglycan, dystrobrevins, syntrophins, sarcospan, caveolin-3, and NO synthase.[ PubMed:15117830 PubMed:16710609 ]
Also Known As "DGC" ; "dystrophin glycoprotein complex"
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_CELLULAR_COMPONENT       6
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Relevant FlyBase reports
 Gene Groups Genes
 dystrophin-associated glycoprotein complex (all annotations which use CV term, excluding "NOT" statements)       2      6
     part_of | dystrophin-associated glycoprotein complex       --       6
Spanning Tree (Parents/Children)
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plasma membrane
 |__plasma membrane protein complex__
protein-containing complex           |
 |__glycoprotein complex_____________|
membrane protein complex             |
 |__plasma membrane protein complex__|
                                     dystrophin-associated glycoprotein complex  13 rec.
                                      |__dystrobrevin complex
                                      |__dystroglycan complex 5 rec.
                                      |   |__sarcoglycan complex 4 rec.
                                      |__syntrophin complex 3 rec.
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Is a glycoprotein complex
plasma membrane protein complex
Part of
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Synonyms
  • "DGC" EXACT
    "dystrophin glycoprotein complex" EXACT
Secondary IDs
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