FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term macroautophagy ID (Ontology) GO:0016236 (Gene Ontology)
Definition The autophagic process that proceeds via the formation of an autophagosome.[ PubMed:24366339 ]
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
    Results list data from multiple species. Click on a button above and use the 'Filter by species' options on the resulting HitList to retrieve species-specific data.
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS      36
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Genes
 macroautophagy (all annotations which use CV term, excluding "NOT" statements)      36
     involved_in | macroautophagy      36
Spanning Tree (Parents/Children)
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catabolic process_______________________
process utilizing autophagic mechanism__|
                                        autophagy
                                         |__macroautophagy  160 rec.
                                             |__aggrephagy 4 rec.
                                             |   |__regulation of aggrephagy(+)
                                             |__amphisome-lysosome fusion
                                             |__autophagosome maturation 34 rec.
                                             |   |__autophagosome membrane docking 1 rec.
                                             |   |__regulation of autophagosome maturation(+) 7 rec.
                                             |__autophagosome organization 45 rec.
                                             |   |__autophagosome assembly(+) 43 rec.
                                             |   |__autophagosome membrane disassembly
                                             |   |__regulation of autophagosome size(+) 2 rec.
                                             |__autophagosome-endosome fusion
                                             |__autophagosome-lysosome fusion 10 rec.
                                             |__glycophagy 13 rec.
                                             |__lipophagy 10 rec.
                                             |   |__regulation of lipophagy(+) 6 rec.
                                             |__lysophagy
                                             |__mitophagy 35 rec.
                                             |   |__regulation of mitophagy(+) 12 rec.
                                             |   |__type 1 mitophagy
                                             |   |__type 2 mitophagy(+) 4 rec.
                                             |__nucleophagy 16 rec.
                                             |   |__piecemeal microautophagy of the nucleus 11 rec.
                                             |__pexophagy 7 rec.
                                             |__proteaphagy
                                             |__regulation of macroautophagy 64 rec.
                                             |   |__negative regulation of macroautophagy(+) 15 rec.
                                             |   |__positive regulation of macroautophagy(+) 45 rec.
                                             |   |__regulation of aggrephagy(+)
                                             |   |__regulation of autophagosome maturation(+) 7 rec.
                                             |   |__regulation of lipophagy(+) 6 rec.
                                             |   |__regulation of mitophagy(+) 12 rec.
                                             |   |__regulation of reticulophagy(+)
                                             |   |__regulation of xenophagy(+)
                                             |__reticulophagy 18 rec.
                                             |   |__regulation of reticulophagy(+)
                                             |__ribophagy 1 rec.
                                             |__xenophagy
                                                 |__regulation of xenophagy(+)
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Is a autophagy
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Synonyms
  • "autophagy" BROAD
    "selective autophagy" NARROW
Secondary IDs
hide External Crossreferences & Linkouts
Reactome:R-HSA-1632852 "Macroautophagy"
Reactome:R-HSA-5205685 "PINK1-PRKN Mediated Mitophagy"
Reactome:R-HSA-8934903 "Receptor Mediated Mitophagy"