FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term eukaryotic translation initiation factor 4F complex ID (Ontology) GO:0016281 (Gene Ontology)
Definition The eukaryotic translation initiation factor 4F complex is composed of eIF4E, eIF4A and eIF4G; it is involved in the recognition of the mRNA cap, ATP-dependent unwinding of the 5'-terminal secondary structure and recruitment of the mRNA to the ribosome.[ PubMed:32883864 PubMed:8449919 ]
Also Known As "cytoplasmic cap-binding complex" ; "eIF-4F"
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_CELLULAR_COMPONENT      12
Genes (FBgn)  GO_MOLECULAR_FUNCTION       1
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 Full annotation statements 
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 Genes
 eukaryotic translation initiation factor 4F complex (all annotations which use CV term, excluding "NOT" statements)      12
     part_of | eukaryotic translation initiation factor 4F complex      12
Spanning Tree (Parents/Children)
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intracellular anatomical structure
 |__cytoplasm_____________________________
cellular anatomical structure             |
 |__cytoplasm_____________________________|
intracellular protein-containing complex  |
 |__RNA cap binding complex_______________|
                                          eukaryotic translation initiation factor 4F complex  12 rec.
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Is a RNA cap binding complex
Part of cytoplasm
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Synonyms
  • "cytoplasmic cap-binding complex" EXACT
    "eIF-4F" EXACT
    "eukaryotic translation initiation factor 4 complex" BROAD
Secondary IDs
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