FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
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Term somatic recombination of immunoglobulin gene segments ID (Ontology) GO:0016447 (Gene Ontology)
Definition The process in which immunoglobulin genes are formed through recombination of the germline genetic elements, as known as immunoglobulin gene segments, within a single locus.[ ISBN:0781735149 ]
Also Known As "somatic recombination of antibody gene segments"
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somatic diversification of immune receptors
 |__somatic diversification of immune receptors via germline recombination within a single locus__
 |__somatic diversification of immunoglobulins____________________________________________________|
immunoglobulin production                                                                         |
 |__somatic diversification of immunoglobulins____________________________________________________|
somatic cell DNA recombination                                                                    |
 |__somatic diversification of immune receptors via germline recombination within a single locus__|
                                                                                         somatic recombination of immunoglobulin gene segments
                                                                                          |__B cell receptor editing
                                                                                          |   |__central B cell receptor editing
                                                                                          |   |__peripheral B cell receptor editing
                                                                                          |__immunoglobulin V(D)J recombination
                                                                                          |   |__immunoglobulin heavy chain V-D-J recombination
                                                                                          |   |__immunoglobulin light chain V-J recombination
                                                                                          |__somatic diversification of immunoglobulin genes by N region addition
                                                                                          |__somatic recombination of immunoglobulin genes involved in immune response
                                                                                              |__isotype switching(+)
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Is a somatic diversification of immune receptors via germline recombination within a single locus
somatic diversification of immunoglobulins
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