FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term protein processing ID (Ontology) GO:0016485 (Gene Ontology)
Definition Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. Protein maturation is the process leading to the attainment of the full functional capacity of a protein.
Also Known As "protein maturation by peptide bond cleavage" ; "protein maturation by peptide bond hydrolysis"
Comment
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS      46
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 protein processing (all annotations which use CV term, excluding "NOT" statements)       3     46
     involved_in | protein processing       --      46
Spanning Tree (Parents/Children)
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protein metabolic process
 |__proteolysis_________
 |__protein maturation__|
                        protein processing  97 rec.
                         |__activation of plasma proteins involved in acute inflammatory response
                         |__CAAX-box protein processing 7 rec.
                         |__dibasic protein processing
                         |   |__arg-arg specific dibasic protein processing
                         |   |__lys-arg specific dibasic protein processing
                         |   |__lys-lys specific dibasic protein processing
                         |__mitochondrial protein processing 10 rec.
                         |   |__protein processing involved in protein targeting to mitochondrion 5 rec.
                         |__Notch receptor processing, ligand-independent
                         |__protein autoprocessing 6 rec.
                         |__protein processing in phagocytic vesicle
                         |__protein splicing 1 rec.
                         |   |__intein-mediated protein splicing 1 rec.
                         |   |__non-intein-mediated protein splicing
                         |__signal peptide processing 9 rec.
                         |   |__SRP-dependent cotranslational protein targeting to membrane, signal sequence processing
                         |__signaling receptor ligand precursor processing 20 rec.
                         |   |__cytokine precursor processing
                         |   |__neuropeptide processing 1 rec.
                         |   |__peptide hormone processing(+) 19 rec.
                         |__vacuolar protein processing 1 rec.
                         |__zymogen activation 9 rec.
                             |__plasminogen activation 1 rec.
                             |__trypsinogen activation
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Is a proteolysis
protein maturation
Part of
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Synonyms
  • "peptidolysis during protein maturation" RELATED
    "protein maturation by peptide bond cleavage" EXACT
    "protein maturation by peptide bond hydrolysis" EXACT
    "protein maturation by proteolysis" RELATED
Secondary IDs
hide External Crossreferences & Linkouts
Reactome:R-HSA-9033500 "TYSND1 cleaves peroxisomal proteins"