FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term peptide hormone processing ID (Ontology) GO:0016486 (Gene Ontology)
Definition The generation of a mature peptide hormone by posttranslational processing of a prohormone.
Comment
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS       5
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 Genes
 peptide hormone processing (all annotations which use CV term, excluding "NOT" statements)       5
     involved_in | peptide hormone processing       5
Spanning Tree (Parents/Children)
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metabolic process
 |__hormone metabolic process_______________________
 |__amide metabolic process_________________________|
regulation of hormone levels                        |
 |__hormone metabolic process_______________________|
protein processing                                  |
 |__signaling receptor ligand precursor processing__|
                                                    peptide hormone processing  19 rec.
                                                     |__angiotensin maturation 3 rec.
                                                     |__endothelin maturation
                                                     |__enkephalin processing
                                                     |__epidermal growth factor receptor ligand maturation 8 rec.
                                                     |__glucagon processing
                                                     |__insulin processing
                                                     |__islet amyloid polypeptide processing
                                                     |__nerve growth factor processing
                                                     |__patched ligand maturation 3 rec.
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Is a hormone metabolic process
amide metabolic process
signaling receptor ligand precursor processing
Part of
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Synonyms
Secondary IDs
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Reactome:R-HSA-209952 "Peptide hormone biosynthesis"
Reactome:R-HSA-400508 "Incretin synthesis, secretion, and inactivation"
Reactome:R-HSA-422085 "Synthesis, secretion, and deacylation of Ghrelin"