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General Information
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| Term |
core-binding factor complex |
ID (Ontology) |
GO:0016513 (Gene Ontology) |
| Definition |
A heterodimeric transcription factor complex that contains an alpha subunit (Runx1, Runx2 or Runx3 in human) that binds DNA and a non-DNA-binding beta subunit (CBFbeta), and binds to a consensus sequence 5'-YGYGGTY-3' found in several enhancers and promoters; the beta subunit enhances the DNA binding of the alpha subunit.[ PubMed:15156179 PubMed:8497254 ] |
| Also Known As |
"CBF complex" |
| Comment |
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Links to External Ontologies
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QuickGO data AmiGO data
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Annotations
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Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
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| Data Class | Field | Records |
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| Genes (FBgn) | GO_CELLULAR_COMPONENT | 2 |
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Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
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| Full annotation statements | Relevant FlyBase reports |
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| Genes |
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core-binding factor complex (all annotations which use CV term, excluding "NOT" statements) | 2 | part_of | core-binding factor complex | 2 |
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Relationships
