General Information
Term	RNA polymerase II, holoenzyme	ID (Ontology)	GO:0016591 (Gene Ontology)
Definition	A nuclear DNA-directed RNA polymerase complex containing an RNA polymerase II core enzyme as well as additional proteins and transcription factor complexes, that are capable of promoter recognition and transcription initiation from an RNA polymerase II promoter in vivo. These additional components may include general transcription factor complexes TFIIA, TFIID, TFIIE, TFIIF, or TFIIH, as well as Mediator, SWI/SNF, GCN5, or SRBs and confer the ability to recognize promoters.[ PubMed:16858867 ]
Also Known As	"DNA-directed RNA polymerase II, holoenzyme"
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General Information

Term

RNA polymerase II, holoenzyme

ID (Ontology)

GO:0016591 (Gene Ontology)

Definition

A nuclear DNA-directed RNA polymerase complex containing an RNA polymerase II core enzyme as well as additional proteins and transcription factor complexes, that are capable of promoter recognition and transcription initiation from an RNA polymerase II promoter in vivo. These additional components may include general transcription factor complexes TFIIA, TFIID, TFIIE, TFIIF, or TFIIH, as well as Mediator, SWI/SNF, GCN5, or SRBs and confer the ability to recognize promoters.[ PubMed:16858867 ]

Also Known As

"DNA-directed RNA polymerase II, holoenzyme"

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

No relevant statements available

DNA-directed RNA polymerase complex__
nucleoplasm__________________________|
nuclear protein-containing complex___|
                                     nuclear DNA-directed RNA polymerase complex
                                      |__RNA polymerase II, holoenzyme  83 rec.
                                          |__Cdc73/Paf1 complex 14 rec.
                                          |__RNA polymerase II, core complex 14 rec.
                                          |__transcription factor TFIIA complex 7 rec.
                                          |__transcription factor TFIID complex 29 rec.
                                          |   |__TAF4B-containing transcription factor TFIID complex
                                          |__transcription factor TFIIE complex 3 rec.
                                          |__transcription factor TFIIF complex 3 rec.
                                          |__transcription factor TFIIH holo complex 13 rec.
                                          |   |__core TFIIH complex portion of holo TFIIH complex 1 rec.
                                          |   |__transcription factor TFIIK complex 2 rec.
                                          |__transcription factor TFTC complex

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Is a	nuclear DNA-directed RNA polymerase complex
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Synonyms & Secondary IDs
Synonyms
	"DNA-directed RNA polymerase II, holoenzyme" EXACT
Secondary IDs

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nuclear DNA-directed RNA polymerase complex

Part of

Synonyms & Secondary IDs

Synonyms

"DNA-directed RNA polymerase II, holoenzyme" EXACT

Secondary IDs

External Crossreferences & Linkouts